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    CLCN6 chloride voltage-gated channel 6 [ Gallus gallus (chicken) ]

    Gene ID: 419488, updated on 6-Jun-2024

    Summary

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    Symbol
    CLCN6provided by CGNC
    Full Name
    chloride voltage-gated channel 6provided by CGNC
    Primary source
    CGNC:3395
    See related
    Ensembl:ENSGALG00010017582
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CLCN6 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (5578073..5598557, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (5612149..5632654, complement)

    Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene renal natriuretic peptide Neighboring gene natriuretic peptide A Neighboring gene methylenetetrahydrofolate reductase Neighboring gene chromosome 1 open reading frame 167 Neighboring gene angiotensin II receptor associated protein Neighboring gene dorsal inhibitory axon guidance protein Neighboring gene mitotic arrest deficient 2 like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloride transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    H(+)/Cl(-) exchange transporter 6; chloride transport protein 6
    Names
    chloride channel 6
    chloride channel, voltage-sensitive 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001285979.2 → NP_001272908.1  H(+)/Cl(-) exchange transporter 6

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000329
      UniProtKB/TrEMBL
      A0A8V0Z261
      Related
      ENSGALP00010024995.1, ENSGALT00010042505.1
      Conserved Domains (5) summary
      smart00116
      Location:607 → 654
      CBS; Domain in cystathionine beta-synthase and other proteins
      COG0517
      Location:802 → 852
      CBS; CBS domain [Signal transduction mechanisms]
      cd03685
      Location:47 → 587
      ClC_6_like; ClC-6-like chloride channel proteins. This CD includes ClC-6, ClC-7 and ClC-B, C, D in plants. Proteins in this family are ubiquitous in eukarotes and their functions are unclear. They are expressed in intracellular organelles membranes. This family ...
      cd04591
      Location:697 → 852
      CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
      pfam00654
      Location:138 → 569
      Voltage_CLC; Voltage gated chloride channel

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5578073..5598557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040651189.1 → XP_040507123.1  chloride transport protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z261
      Conserved Domains (3) summary
      COG3448
      Location:654 → 830
      COG3448; CBS-domain-containing membrane protein [Signal transduction mechanisms]
      cd03685
      Location:23 → 563
      ClC_6_like; ClC-6-like chloride channel proteins. This CD includes ClC-6, ClC-7 and ClC-B, C, D in plants. Proteins in this family are ubiquitous in eukarotes and their functions are unclear. They are expressed in intracellular organelles membranes. This family ...
      cd04591
      Location:575 → 831
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5612149..5632654 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046931321.1 → XP_046787277.1  chloride transport protein 6 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z261
    Nucleotide Protein
    Heading Accession and Version

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