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    SAV1 salvador family WW domain containing protein 1 [ Gallus gallus (chicken) ]

    Gene ID: 423578, updated on 5-Mar-2024

    Summary

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    Symbol
    SAV1provided by CGNC
    Full Name
    salvador family WW domain containing protein 1provided by CGNC
    Primary source
    CGNC:9373
    See related
    Ensembl:ENSGALG00010019350
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See SAV1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (57655415..57666791, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (57530332..57541646, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 5 Neighboring gene atlastin GTPase 1 Neighboring gene ninein Neighboring gene abhydrolase domain containing 12B Neighboring gene phosphorylase, glycogen, liver

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Hippo/MST Pathway Member SAV1 Plays a Suppressive Role in Development of the Prehierarchical Follicles in Hen Ovary. Lyu Z, et al. PLoS One, 2016. PMID 27505353, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SAV1 can inhibit proliferation of the granulosa cells
      Title: The Hippo/MST Pathway Member SAV1 Plays a Suppressive Role in Development of the Prehierarchical Follicles in Hen Ovary.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables molecular adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein salvador homolog 1
    Names
    salvador homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      57655415..57666791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015276749.4 → XP_015132235.1  protein salvador homolog 1 isoform X1

      UniProtKB/TrEMBL
      E1C3T7
      Related
      ENSGALP00010027863.1, ENSGALT00010046802.1
      Conserved Domains (1) summary
      cd00201
      Location:204 → 234
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...

    2. XM_040701820.2 → XP_040557754.1  protein salvador homolog 1 isoform X2

      Conserved Domains (1) summary
      cd00201
      Location:204 → 234
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      57530332..57541646 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040672873.2 → XP_040528807.1  protein salvador homolog 1 isoform X1

      UniProtKB/TrEMBL
      E1C3T7

    2. XM_040672874.2 → XP_040528808.1  protein salvador homolog 1 isoform X2

      Conserved Domains (1) summary
      cd00201
      Location:204 → 234
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    Nucleotide Protein Strain
    Heading Accession and Version

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