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    PF3D7_0802600 adenylyl cyclase beta [ Plasmodium falciparum 3D7 ]

    Gene ID: 2655397, updated on 17-May-2024

    Summary

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    Gene symbol
    PF3D7_0802600
    Gene description
    adenylyl cyclase beta
    Primary source
    PlasmoDB:PF3D7_0802600
    Locus tag
    PF3D7_0802600
    See related
    VEuPathDB:PF3D7_0802600
    Gene type
    protein coding
    RNA name
    adenylyl cyclase beta
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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    Genomic context

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    See PF3D7_0802600 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    5
    Sequence:
    Chromosome: 8; NC_004329.3 (180563..188113)

    Chromosome 8 - NC_004329.3Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene inositol 5-phosphatase, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene serine/threonine protein phosphatase 2B catalytic subunit A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004329.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery. Patel A, et al. PLoS Biol, 2019 May. PMID 31075098, Free PMC Article
    2. The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes. Dawn A, et al. PLoS Pathog, 2014 Dec. PMID 25522250, Free PMC Article
    3. Characterization of Plasmodium falciparum adenylyl cyclase-β and its role in erythrocytic stage parasites. Salazar E, et al. PLoS One, 2012. PMID 22761895, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables adenylate cyclase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to pH IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in rhoptry IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenylyl cyclase beta
    XP_002808810.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004329.3 Reference assembly

      Range
      180563..188113
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002808764.1 → XP_002808810.1  adenylyl cyclase beta [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_002808810.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0L7LW10, A0A2I0BWZ2, C0H4R1
      Conserved Domains (2) summary
      cd07302
      Location:611 → 778
      CHD; cyclase homology domain
      cl11967
      Location:114 → 176
      Nucleotidyl_cyc_III; Class III nucleotidyl cyclases
    Nucleotide Protein
    Heading Accession and Version

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