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    SPOP speckle type BTB/POZ protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699711, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SPOPprovided by VGNC
    Official Full Name
    speckle type BTB/POZ proteinprovided by VGNC
    Primary source
    VGNC:VGNC:77863
    Locus tag
    EGK_08504
    See related
    Ensembl:ENSMMUG00000018752
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPOP in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (47113121..47196882)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (39875769..39959415)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 117 member A Neighboring gene solute carrier family 35 member B1 Neighboring gene neurexophilin 3 Neighboring gene nerve growth factor receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    speckle-type POZ protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001258173.2 → NP_001245102.1  speckle-type POZ protein

      See identical proteins and their annotated locations for NP_001245102.1

      Status: PROVISIONAL

      Source sequence(s)
      JU472236
      UniProtKB/TrEMBL
      A0A1D5RGQ4, A0A8J8XVE9, F6XVE8, G7NHF1
      Related
      ENSMMUP00000024681.2, ENSMMUT00000026366.4
      Conserved Domains (3) summary
      cd03774
      Location:28 → 166
      MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
      cd18279
      Location:182 → 301
      BTB_POZ_SPOP-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein (SPOP) and similar proteins
      cd18518
      Location:297 → 367
      BACK_SPOP; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein (SPOP)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      47113121..47196882
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835498.1 → XP_028691331.1  speckle-type POZ protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5RGQ4, A0A8J8XVE9, F6XVE8, G7NHF1
      Related
      ENSMMUP00000079699.1, ENSMMUT00000104217.1
      Conserved Domains (3) summary
      cd03774
      Location:28 → 166
      MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
      cd18279
      Location:182 → 301
      BTB_POZ_SPOP-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein (SPOP) and similar proteins
      cd18518
      Location:297 → 367
      BACK_SPOP; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein (SPOP)

    2. XM_015119242.2 → XP_014974728.1  speckle-type POZ protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5RGQ4, A0A8J8XVE9, F6XVE8, G7NHF1
      Conserved Domains (3) summary
      cd03774
      Location:28 → 166
      MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
      cd18279
      Location:182 → 301
      BTB_POZ_SPOP-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein (SPOP) and similar proteins
      cd18518
      Location:297 → 367
      BACK_SPOP; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein (SPOP)

    3. XM_015119238.2 → XP_014974724.1  speckle-type POZ protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5RGQ4, A0A8J8XVE9, F6XVE8, G7NHF1
      Related
      ENSMMUP00000078898.1, ENSMMUT00000106603.1
      Conserved Domains (3) summary
      cd03774
      Location:28 → 166
      MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
      cd18279
      Location:182 → 301
      BTB_POZ_SPOP-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein (SPOP) and similar proteins
      cd18518
      Location:297 → 367
      BACK_SPOP; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein (SPOP)

    4. XM_015119237.1 → XP_014974723.1  speckle-type POZ protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5RGQ4, A0A8J8XVE9, F6XVE8, G7NHF1
      Related
      ENSMMUP00000070408.1, ENSMMUT00000090617.1
      Conserved Domains (3) summary
      cd03774
      Location:28 → 166
      MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
      cd18279
      Location:182 → 301
      BTB_POZ_SPOP-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein (SPOP) and similar proteins
      cd18518
      Location:297 → 367
      BACK_SPOP; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein (SPOP)

    5. XM_028835499.1 → XP_028691332.1  speckle-type POZ protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5RGQ4, A0A8J8XVE9, F6XVE8, G7NHF1
      Conserved Domains (3) summary
      cd03774
      Location:28 → 166
      MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
      cd18279
      Location:182 → 301
      BTB_POZ_SPOP-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein (SPOP) and similar proteins
      cd18518
      Location:297 → 367
      BACK_SPOP; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein (SPOP)

    6. XM_028835500.1 → XP_028691333.1  speckle-type POZ protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5RGQ4, A0A8J8XVE9, F6XVE8, G7NHF1
      Related
      ENSMMUP00000063561.1, ENSMMUT00000095128.1
      Conserved Domains (3) summary
      cd03774
      Location:28 → 166
      MATH_SPOP; Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled ...
      cd18279
      Location:182 → 301
      BTB_POZ_SPOP-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein (SPOP) and similar proteins
      cd18518
      Location:297 → 367
      BACK_SPOP; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein (SPOP)
    Nucleotide Protein
    Heading Accession and Version

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