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    TOX thymocyte selection associated high mobility group box [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698759, updated on 5-Mar-2024

    Summary

    Official Symbol
    TOXprovided by VGNC
    Official Full Name
    thymocyte selection associated high mobility group boxprovided by VGNC
    Primary source
    VGNC:VGNC:79165
    See related
    Ensembl:ENSMMUG00000010971
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See TOX in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (59450801..59761053, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (56814457..57127005, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114680254 Neighboring gene small nucleolar RNA U13 Neighboring gene neutral sphingomyelinase activation associated factor Neighboring gene U4 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA51 Neighboring gene carbonic anhydrase 8

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin DNA binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in leukocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    thymocyte selection-associated high mobility group box protein TOX

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261489.2NP_001248418.1  thymocyte selection-associated high mobility group box protein TOX

      See identical proteins and their annotated locations for NP_001248418.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045426
      UniProtKB/TrEMBL
      F7GDG8, H9F9J6, I0FM21
      Related
      ENSMMUP00000014382.3, ENSMMUT00000015350.4
      Conserved Domains (2) summary
      COG5648
      Location:257360
      NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
      cd00084
      Location:261310
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      59450801..59761053 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028852140.1XP_028707973.1  thymocyte selection-associated high mobility group box protein TOX isoform X1

      UniProtKB/TrEMBL
      F7GDG8
      Conserved Domains (2) summary
      COG5648
      Location:235338
      NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
      cd00084
      Location:239288
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...