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    Mrpl49 mitochondrial ribosomal protein L49 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309176, updated on 13-Apr-2024

    Summary

    Official Symbol
    Mrpl49provided by RGD
    Official Full Name
    mitochondrial ribosomal protein L49provided by RGD
    Primary source
    RGD:1309920
    See related
    Ensembl:ENSRNOG00000020975 AllianceGenome:RGD:1309920
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Aa2-277
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL49 (mitochondrial ribosomal protein L49). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 274.3), Brain (RPKM 233.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mrpl49 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212775357..212779364, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (203346068..203350040, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (221417336..221420115, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 20 Neighboring gene calpain 1 Neighboring gene uncharacterized LOC108349685 Neighboring gene synoviolin 1 Neighboring gene zinc finger, HIT-type containing 2 Neighboring gene FAU ubiquitin like and ribosomal protein S30 fusion

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein mL49
    Names
    39S ribosomal protein L49, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001047883.2NP_001041348.1  large ribosomal subunit protein mL49

      See identical proteins and their annotated locations for NP_001041348.1

      Status: VALIDATED

      Source sequence(s)
      FM121128, JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6AG94, A6HZC2, Q7TP77
      Related
      ENSRNOP00000092288.1, ENSRNOT00000115949.1
      Conserved Domains (1) summary
      pfam05046
      Location:82161
      Img2; Mitochondrial large subunit ribosomal protein (Img2)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      212775357..212779364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264399.1XP_063120469.1  large ribosomal subunit protein mL49 isoform X1