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    Rbm26 RNA binding motif protein 26 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306137, updated on 19-Jun-2024

    Summary

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    Official Symbol
    Rbm26provided by RGD
    Official Full Name
    RNA binding motif protein 26provided by RGD
    Primary source
    RGD:1308297
    See related
    Ensembl:ENSRNOG00000009836 AllianceGenome:RGD:1308297
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308297
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be active in nucleus. Orthologous to human RBM26 (RNA binding motif protein 26). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 247.1), Spleen (RPKM 212.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rbm26 in Genome Data Viewer
    Location:
    15q22
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (88299378..88379365, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (81884783..81964245, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (89262683..89339323, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC108352963 Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene ribosomal protein S11, pseudogene 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Docking motif-guided mapping of the interactome of protein phosphatase-1. Hendrickx A, et al. Chem Biol, 2009 Apr 24. PMID 19389623
    2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein 26

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001277160.1 → NP_001264089.1  RNA-binding protein 26

      See identical proteins and their annotated locations for NP_001264089.1

      Status: VALIDATED

      Source sequence(s)
      BC082039, FN801746, JAXUCZ010000015
      UniProtKB/TrEMBL
      A0A8I5Y1B1
      Related
      ENSRNOP00000013297.7, ENSRNOT00000013297.8
      Conserved Domains (5) summary
      smart00356
      Location:294 → 314
      ZnF_C3H1; zinc finger
      COG0419
      Location:708 → 830
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd12258
      Location:872 → 943
      RRM2_RBM26_like; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 26 (RBM26) and similar proteins
      cd12516
      Location:541 → 616
      RRM1_RBM26; RNA recognition motif 1 (RRM1) found in vertebrate RNA-binding protein 26 (RBM26)
      cl02562
      Location:11 → 76
      PWI; PWI domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      88299378..88379365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006252425.4 → XP_006252487.1  RNA-binding protein 26 isoform X3

      UniProtKB/TrEMBL
      A0A8I5Y1B1
      Related
      ENSRNOP00000013255.6
      Conserved Domains (6) summary
      smart00356
      Location:294 → 314
      ZnF_C3H1; zinc finger
      cd12258
      Location:896 → 967
      RRM2_RBM26_like; RNA recognition motif 2 of vertebrate RNA-binding protein 26 (RBM26) and similar proteins
      cd12516
      Location:541 → 616
      RRM1_RBM26; RNA recognition motif 1 of vertebrate RNA-binding protein 26 (RBM26)
      pfam08648
      Location:132 → 165
      DUF1777; Protein of unknown function (DUF1777)
      pfam13864
      Location:748 → 829
      Enkurin; Calmodulin-binding
      cl02562
      Location:11 → 76
      PWI; PWI domain

    2. XM_063274339.1 → XP_063130409.1  RNA-binding protein 26 isoform X6

      UniProtKB/TrEMBL
      A0A8I6AB29

    3. XM_063274337.1 → XP_063130407.1  RNA-binding protein 26 isoform X4

      UniProtKB/TrEMBL
      A0A8I6AB29, D3ZRG7

    4. XM_063274336.1 → XP_063130406.1  RNA-binding protein 26 isoform X2

      UniProtKB/TrEMBL
      D3ZRC3

    5. XM_039093404.2 → XP_038949332.1  RNA-binding protein 26 isoform X1

      UniProtKB/TrEMBL
      D3ZRC3
      Conserved Domains (5) summary
      smart00356
      Location:294 → 314
      ZnF_C3H1; zinc finger
      COG0419
      Location:732 → 854
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd12258
      Location:896 → 967
      RRM2_RBM26_like; RNA recognition motif 2 (RRM2) found in vertebrate RNA-binding protein 26 (RBM26) and similar proteins
      cd12516
      Location:541 → 616
      RRM1_RBM26; RNA recognition motif 1 (RRM1) found in vertebrate RNA-binding protein 26 (RBM26)
      cl02562
      Location:11 → 76
      PWI; PWI domain

    6. XM_063274338.1 → XP_063130408.1  RNA-binding protein 26 isoform X5

      UniProtKB/TrEMBL
      D3ZRC3

    7. XM_063274341.1 → XP_063130411.1  RNA-binding protein 26 isoform X8

    8. XM_063274340.1 → XP_063130410.1  RNA-binding protein 26 isoform X7

    RNA

    1. XR_010057829.1 RNA Sequence

    2. XR_010057830.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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