S100z S100 calcium binding protein, zeta [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: S100zprovided by MGI
Official Full Name: S100 calcium binding protein, zetaprovided by MGI
Primary source: MGI:MGI:2685471
See related: Ensembl:ENSMUSG00000021679 AllianceGenome:MGI:2685471
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm625
Summary: Predicted to enable calcium ion binding activity; calcium-dependent protein binding activity; and protein homodimerization activity. Orthologous to human S100Z (S100 calcium binding protein Z). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in genital fat pad adult (RPKM 6.1) and testis adult (RPKM 0.5) See more
Orthologs: human all
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Genomic context

Location:: 13 D1; 13 49.53 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (95613809..95615163, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (95477301..95478655, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	ISO Inferred from Sequence Orthology more info
enables calcium-dependent protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables molecular_function	ND No biological Data available more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: protein S100-Z

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001081159.1 → NP_001074628.1 protein S100-Z

See identical proteins and their annotated locations for NP_001074628.1

Status: PROVISIONAL

Source sequence(s)

AC159263

Consensus CDS

CCDS36752.1

UniProtKB/TrEMBL

B9EJL3

Related

ENSMUSP00000022186.4, ENSMUST00000022186.5

Conserved Domains (2) summary

pfam13499
Location:25 → 79

EF-hand_7; EF-hand domain pair

cl08302
Location:1 → 93

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...