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    Ir52d Ionotropic receptor 52d [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36716, updated on 10-May-2024

    Summary

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    Official Symbol
    Ir52dprovided by FlyBase
    Official Full Name
    Ionotropic receptor 52dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050464
    Locus tag
    Dmel_CG30464
    See related
    AllianceGenome:FB:FBgn0050464
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    52d; CG12961; CG30464; DmelIR52d; Dmel\CG30464; IR52d
    Summary
    Predicted to enable ligand-gated ion channel activity. Involved in reproductive behavior. Predicted to be integral component of membrane. Is expressed in mesothoracic leg taste bristle chemosensory neurons; metathoracic leg taste bristle chemosensory neurons; prothoracic leg; prothoracic leg taste bristle chemosensory neurons; and prothoracic tarsal bristle. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See Ir52d in Genome Data Viewer
    Location:
    52A6-52A6; 2-74 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15506582..15508366)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11394087..11395871)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 52b Neighboring gene Ionotropic receptor 52c Neighboring gene Polypeptide N-Acetylgalactosaminyltransferase 1 Neighboring gene Kinesin heavy chain 73

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pheromone processing in Drosophila. Kohl J, et al. Curr Opin Neurobiol, 2015 Oct. PMID 26143522, Free PMC Article
    2. Sexual circuitry in Drosophila. Auer TO, et al. Curr Opin Neurobiol, 2016 Jun. PMID 26851712
    3. Calcium Taste Avoidance in Drosophila. Lee Y, et al. Neuron, 2018 Jan 3. PMID 29276056, Free PMC Article
    4. Candidate ionotropic taste receptors in the Drosophila larva. Stewart S, et al. Proc Natl Acad Sci U S A, 2015 Apr 7. PMID 25825777, Free PMC Article
    5. The Drosophila IR20a clade of ionotropic receptors are candidate taste and pheromone receptors. Koh TW, et al. Neuron, 2014 Aug 20. PMID 25123314, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in reproductive behavior IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 52d
    Names
    CG30464-PB
    Ir52d-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15506582..15508366
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137198.2 → NP_611042.2  ionotropic receptor 52d [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611042.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A077DBM8, A1ZA17
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZA17 A1ZA17

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