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    TM4SF Transmembrane 4 superfamily [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37786, updated on 10-May-2024

    Summary

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    Official Symbol
    TM4SFprovided by FlyBase
    Official Full Name
    Transmembrane 4 superfamilyprovided by FlyBase
    Primary source
    FLYBASE:FBgn0020372
    Locus tag
    Dmel_CG11303
    See related
    AllianceGenome:FB:FBgn0020372
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11303; Dm.Tsp60A; Dmel\CG11303
    Summary
    Predicted to be integral component of membrane. Is expressed in adult head; amnioserosa; embryonic/larval crystal cell; procrystal cell; and yolk nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See TM4SF in Genome Data Viewer
    Location:
    60A7-60A7; 2-105 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23878197..23880860)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19765720..19768383)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Mitochondrial trifunctional protein beta subunit Neighboring gene ken and barbie Neighboring gene uncharacterized protein Neighboring gene Putative homeodomain protein Neighboring gene uncharacterized protein Neighboring gene Decapping protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane 4 superfamily
    Names
    CG11303-PA
    CG11303-PB
    CG11303-PC
    TM4SF-PA
    TM4SF-PB
    TM4SF-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23878197..23880860
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274230.1 → NP_001261159.1  transmembrane 4 superfamily, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261159.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFZ4, Q9UAI4
      Conserved Domains (2) summary
      cd03156
      Location:111 → 197
      uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:9 → 224
      Tetraspannin; Tetraspanin family

    2. NM_001038879.2 → NP_001033968.1  transmembrane 4 superfamily, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033968.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2MGN3

    3. NM_057900.4 → NP_477248.1  transmembrane 4 superfamily, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477248.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76137, Q9UAI4
      Related
      FBpp0072039
      Conserved Domains (1) summary
      pfam00335
      Location:10 → 224
      Tetraspannin; Tetraspanin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFZ4 A0A0B4KFZ4
    O76137 O76137
    Q2MGN3 Q2MGN3
    Q95SQ6 Q95SQ6
    Q9UAI4 Q9UAI4

    Gene LinkOut

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