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    CG17002 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35610, updated on 10-May-2024

    Summary

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    Official Symbol
    CG17002provided by FlyBase
    Primary source
    FLYBASE:FBgn0033122
    Locus tag
    Dmel_CG17002
    See related
    AllianceGenome:FB:FBgn0033122
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17002
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Is expressed in organism. Orthologous to human GPS2 (G protein pathway suppressor 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG17002 in Genome Data Viewer
    Location:
    42E1-42E1; 2-55 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6986043..6988922)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2873548..2876427)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene visceral mesodermal armadillo-repeats Neighboring gene long non-coding RNA:CR44171 Neighboring gene uncharacterized protein Neighboring gene Tetraspanin 42Ea Neighboring gene uncharacterized protein Neighboring gene Tetraspanin 42Eb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of transcriptional targets of the dual-function transcription factor/phosphatase eyes absent. Jemc J, et al. Dev Biol, 2007 Oct 15. PMID 17714699, Free PMC Article
    2. Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity. Kanuka H, et al. Biochim Biophys Acta, 2005 Nov 30. PMID 16243437
    3. Systematic identification and characterization of repressive domains in Drosophila transcription factors. Klaus L, et al. EMBO J, 2023 Feb 1. PMID 36545802, Free PMC Article
    4. A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Lin H, et al. Proc Natl Acad Sci U S A, 2005 Sep 6. PMID 16129837, Free PMC Article
    5. Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster. Manta AK, et al. Fly (Austin), 2017 Apr 3. PMID 27960592, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17002-PB
    CG17002-PC
    CG17002-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6986043..6988922
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136409.3 → NP_610253.1  uncharacterized protein Dmel_CG17002, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610253.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JQT8
      Related
      FBpp0085502
      Conserved Domains (1) summary
      pfam15991
      Location:23 → 271
      G_path_suppress; G-protein pathway suppressor

    2. NM_001201943.2 → NP_001188872.1  uncharacterized protein Dmel_CG17002, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188872.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JCR9
      Conserved Domains (1) summary
      pfam15991
      Location:23 → 271
      G_path_suppress; G-protein pathway suppressor

    3. NM_001201942.2 → NP_001188871.1  uncharacterized protein Dmel_CG17002, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JD24
      Conserved Domains (1) summary
      pfam15991
      Location:23 → 254
      G_path_suppress; G-protein pathway suppressor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JCR9 A0A0B4JCR9
    A0A0B4JD24 A0A0B4JD24
    Q7JQT8 Q7JQT8

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