Eef1g eukaryotic translation elongation factor 1 gamma [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Eef1gprovided by RGD
Official Full Name: eukaryotic translation elongation factor 1 gammaprovided by RGD
Primary source: RGD:1302939
See related: Ensembl:ENSRNOG00000020075 AllianceGenome:RGD:1302939
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable translation elongation factor activity. Predicted to be involved in response to virus and translational elongation. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with endoplasmic reticulum. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Muscle (RPKM 2690.0), Spleen (RPKM 2395.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q43

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (215289815..215300421)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (205860713..205871319)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (225163391..225173997)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

UniSTS:493314 (e-PCR)
- UniSTS:493314

RH131360 (e-PCR)
- UniSTS:214643

RH125672 (e-PCR)
- UniSTS:162453

ksks40 (e-PCR)
- UniSTS:514453

RH15603 (e-PCR)
- UniSTS:84660

RH143146 (e-PCR)
- UniSTS:232393

MARC_5385-5386:991939571:3 (e-PCR)
- UniSTS:231150

Eef1g (e-PCR), detects polymorphism
- UniSTS:526073

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in response to virus	ISO Inferred from Sequence Orthology more info
involved_in translational elongation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: elongation factor 1-gamma

Names: EF-1-gamma; eEF-1B gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004223.2 → NP_001004223.1 elongation factor 1-gamma

See identical proteins and their annotated locations for NP_001004223.1

Status: PROVISIONAL

Source sequence(s)

BC098895

UniProtKB/Swiss-Prot

Q4FZZ5, Q68FR6

UniProtKB/TrEMBL

A0A8I6AK06, A6HZY2

Related

ENSRNOP00000027305.4, ENSRNOT00000027305.8

Conserved Domains (4) summary

cd03181
Location:91 → 213

GST_C_EF1Bgamma_like; Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins

cd03044
Location:4 → 82

GST_N_EF1Bgamma; GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of ...

TIGR01262
Location:5 → 187

maiA; maleylacetoacetate isomerase

pfam00647
Location:275 → 381

EF1G; Elongation factor 1 gamma, conserved domain