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    Abhd1 abhydrolase domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313917, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Abhd1provided by RGD
    Official Full Name
    abhydrolase domain containing 1provided by RGD
    Primary source
    RGD:1310988
    See related
    Ensembl:ENSRNOG00000025689 AllianceGenome:RGD:1310988
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acetylesterase activity and acylglycerol lipase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process and medium-chain fatty acid catabolic process. Predicted to be integral component of membrane. Orthologous to human ABHD1 (abhydrolase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 168.4), Liver (RPKM 149.8) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    6q14
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (31142476..31147464, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (25422526..25427514, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (26787807..26792795, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene transcription factor 23 Neighboring gene proline rich 30 Neighboring gene prolactin regulatory element binding Neighboring gene cell growth regulator with EF hand domain 1 Neighboring gene ketohexokinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105659

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acetylesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables acylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in medium-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in medium-chain fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein ABHD1
    Names
    abhydrolase domain-containing protein 1
    alpha/beta hydrolase domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008520.1 → NP_001008520.1  protein ABHD1

      See identical proteins and their annotated locations for NP_001008520.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086351
      UniProtKB/Swiss-Prot
      Q5RK23
      UniProtKB/TrEMBL
      A6HAA3
      Related
      ENSRNOP00000009339.2, ENSRNOT00000010403.5
      Conserved Domains (1) summary
      cl21494
      Location:54 → 381
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      31142476..31147464 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039112176.2 → XP_038968104.1  protein ABHD1 isoform X1

      UniProtKB/TrEMBL
      A6HAA4
      Conserved Domains (1) summary
      cl21494
      Location:26 → 190
      Abhydrolase; alpha/beta hydrolases

    2. XM_063261874.1 → XP_063117944.1  protein ABHD1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5RK23.1 GenPept UniProtKB/Swiss-Prot:Q5RK23

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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