Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ppan peter pan homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298699, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ppanprovided by RGD
    Official Full Name
    peter pan homologprovided by RGD
    Primary source
    RGD:1306325
    See related
    Ensembl:ENSRNOG00000020608 AllianceGenome:RGD:1306325
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable rRNA binding activity. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Orthologous to several human genes including PPAN-P2RY11 (PPAN-P2RY11 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 147.7), Spleen (RPKM 126.8) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    8q13
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (27700147..27704127)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (19423908..19427941)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (21905865..21909845)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene retinol dehydrogenase 8 Neighboring gene shiftless antiviral inhibitor of ribosomal frameshifting Neighboring gene angiopoietin-like 6 Neighboring gene small nucleolar RNA, C/D box 105B Neighboring gene small nucleolar RNA, C/D box 105 Neighboring gene eukaryotic translation initiation factor 3, subunit G Neighboring gene DNA methyltransferase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Large-scale characterization of HeLa cell nuclear phosphoproteins. Beausoleil SA, et al. Proc Natl Acad Sci U S A, 2004 Aug 17. PMID 15302935, Free PMC Article
    2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC108837

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal large subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    suppressor of SWI4 1 homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011980.1 → NP_001011980.1  suppressor of SWI4 1 homolog

      See identical proteins and their annotated locations for NP_001011980.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089842
      UniProtKB/TrEMBL
      E9PTU3, Q5FVQ2
      Related
      ENSRNOP00000027974.5, ENSRNOT00000027973.6
      Conserved Domains (2) summary
      smart00879
      Location:32 → 221
      Brix; The Brix domain is found in a number of eukaryotic proteins
      pfam04147
      Location:303 → 401
      Nop14; Nop14-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      27700147..27704127
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039080980.2 → XP_038936908.1  suppressor of SWI4 1 homolog isoform X1

      Conserved Domains (2) summary
      smart00879
      Location:6 → 92
      Brix; The Brix domain is found in a number of eukaryotic proteins
      pfam04147
      Location:174 → 272
      Nop14; Nop14-like family
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous