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    Zfp367 zinc finger protein 367 [ Mus musculus (house mouse) ]

    Gene ID: 238673, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Zfp367provided by MGI
    Official Full Name
    zinc finger protein 367provided by MGI
    Primary source
    MGI:MGI:2442266
    See related
    Ensembl:ENSMUSG00000044934 AllianceGenome:MGI:2442266
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ZFF29a; ZFF29b; Znf367; 8030486J21Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Is expressed in several structures, including early conceptus; gonad; immune system; liver; and lung. Orthologous to human ZNF367 (zinc finger protein 367). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver E14 (RPKM 9.6), liver E14.5 (RPKM 8.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    13 B3; 13 33.26 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (64280836..64301013, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (64133022..64153199, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene hydroxysteroid (17-beta) dehydrogenase 3 Neighboring gene solute carrier family 35, member D2 Neighboring gene STARR-seq mESC enhancer starr_34820 Neighboring gene STARR-positive B cell enhancer ABC_E5404 Neighboring gene STARR-positive B cell enhancer ABC_E928 Neighboring gene STARR-positive B cell enhancer ABC_E7250 Neighboring gene hyaluronic acid binding protein 4 Neighboring gene CDC14 cell division cycle 14B Neighboring gene predicted gene, 46424

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and characterization of ZFF29: a protein containing a unique Cys2His2 zinc-finger motif. Asano H, et al. Biochem J, 2004 Dec 15. PMID 15344908, Free PMC Article
    2. Atypical E2F repressors and activators coordinate placental development. Ouseph MM, et al. Dev Cell, 2012 Apr 17. PMID 22516201, Free PMC Article
    3. Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Ulmke PA, et al. Stem Cell Reports, 2021 Apr 13. PMID 33798452, Free PMC Article
    4. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    5. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 367
    Names
    C2H2 zinc finger protein ZFF29

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361047.1 → NP_001347976.1  zinc finger protein 367 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC158990, CT009717
      Conserved Domains (2) summary
      COG5048
      Location:43 → 116
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:45 → 65
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_175494.5 → NP_780703.1  zinc finger protein 367 isoform 1

      See identical proteins and their annotated locations for NP_780703.1

      Status: VALIDATED

      Source sequence(s)
      AC158990, CT009717
      Consensus CDS
      CCDS26596.1
      UniProtKB/Swiss-Prot
      B1B191, B1B192, Q0VDT2, Q8BH90, Q8BI44, Q8BI88
      Related
      ENSMUSP00000050854.5, ENSMUST00000059817.12
      Conserved Domains (2) summary
      COG5048
      Location:157 → 230
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:159 → 179
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      64280836..64301013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VDT2.2 GenPept UniProtKB/Swiss-Prot:Q0VDT2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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