Pcbp3 poly(rC) binding protein 3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pcbp3provided by MGI
Official Full Name: poly(rC) binding protein 3provided by MGI
Primary source: MGI:MGI:1890470
See related: Ensembl:ENSMUSG00000001120 AllianceGenome:MGI:1890470
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: AlphaCP-3
Summary: Enables C-rich single-stranded DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and double-stranded DNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PCBP3 (poly(rC) binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 58.9), frontal lobe adult (RPKM 37.3) and 13 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 C1; 10 39.72 cM

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (76597688..76797951, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (76761854..76962117, complement)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This study demonstrates for the first time that PCBP3 can function as a repressor dependent on binding to single-strand and double-stranded poly(C) sequences.
Title: Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence.
Represses mu opioid receptor gene promoter at the transcriptional level.
Title: Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Pcbp3 (e-PCR), detects polymorphism
- UniSTS:259123

RH129104 (e-PCR)
- UniSTS:212412

D10Mit242 (e-PCR), detects polymorphism
- UniSTS:126147

Pcbp3 (e-PCR), detects polymorphism
- UniSTS:479191

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables C-rich single-stranded DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: poly(rC)-binding protein 3

Names: alpha-CP3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001347216.2 → NP_001334145.1 poly(rC)-binding protein 3 isoform 2

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276

Consensus CDS

CCDS83716.1

UniProtKB/Swiss-Prot

P57722

Conserved Domains (2) summary

cd00105
Location:294 → 356

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
NM_001429299.1 → NP_001416228.1 poly(rC)-binding protein 3 isoform 1

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NM_001429300.1 → NP_001416229.1 poly(rC)-binding protein 3 2

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NM_001429301.1 → NP_001416230.1 poly(rC)-binding protein 3 isoform 3

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NM_001429302.1 → NP_001416231.1 poly(rC)-binding protein 3 isoform 3

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NM_001429303.1 → NP_001416232.1 poly(rC)-binding protein 3 isoform 4

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NM_001429304.1 → NP_001416233.1 poly(rC)-binding protein 3 isoform 5

Status: VALIDATED

Source sequence(s)

AC168275, AC168276
NM_001429305.1 → NP_001416234.1 poly(rC)-binding protein 3 isoform 5

Status: VALIDATED

Source sequence(s)

AC168276
NM_001429306.1 → NP_001416235.1 poly(rC)-binding protein 3 isoform 6

Status: VALIDATED

Source sequence(s)

AC168275, AC168276
NM_001429307.1 → NP_001416236.1 poly(rC)-binding protein 3 isoform 7

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NM_001429308.1 → NP_001416237.1 poly(rC)-binding protein 3 isoform 8

Status: VALIDATED

Source sequence(s)

AC168275, AC168276
NM_001429309.1 → NP_001416238.1 poly(rC)-binding protein 3 isoform 9

Status: VALIDATED

Source sequence(s)

AC168276
NM_001429310.1 → NP_001416239.1 poly(rC)-binding protein 3 isoform 10

Status: VALIDATED

Source sequence(s)

AC168276
NM_001429311.1 → NP_001416240.1 poly(rC)-binding protein 3 isoform 11

Status: VALIDATED

Source sequence(s)

AC168276
NM_001429312.1 → NP_001416241.1 poly(rC)-binding protein 3 isoform 12

Status: VALIDATED

Source sequence(s)

AC168276
NM_021568.3 → NP_067543.2 poly(rC)-binding protein 3 isoform 1

See identical proteins and their annotated locations for NP_067543.2

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276

Consensus CDS

CCDS35946.2

UniProtKB/Swiss-Prot

P57722, Q8BSB0, Q8C544

Related

ENSMUSP00000001148.5, ENSMUST00000001148.11

Conserved Domains (3) summary

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:286 → 360

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cl00098
Location:38 → 114

KH-I; K homology (KH) RNA-binding domain, type I

RNA

NR_152849.2 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168275, AC168276

Related

ENSMUST00000168505.8
NR_152850.2 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168276
NR_190709.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168276
NR_190710.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NR_190711.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NR_190712.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168275, AC168276
NR_190713.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168276
NR_190714.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NR_190715.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NR_190716.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168276
NR_190717.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168275, AC168276
NR_190718.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC168275, AC168276
NR_190719.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276
NR_190720.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC055777, AC168275, AC168276

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000076.7 Reference GRCm39 C57BL/6J

Range

76597688..76797951 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006513926.4 → XP_006513989.1 poly(rC)-binding protein 3 isoform X10

Conserved Domains (2) summary

cd00105
Location:274 → 336

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_006513925.4 → XP_006513988.1 poly(rC)-binding protein 3 isoform X9

Conserved Domains (2) summary

cd00105
Location:275 → 337

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_006513922.4 → XP_006513985.1 poly(rC)-binding protein 3 isoform X4

Conserved Domains (2) summary

cd00105
Location:297 → 359

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_006513920.4 → XP_006513983.1 poly(rC)-binding protein 3 isoform X2

Conserved Domains (4) summary

pfam03154
Location:181 → 314

Atrophin-1; Atrophin-1 family

cd22516
Location:38 → 114

KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:308 → 382

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
XM_006513921.4 → XP_006513984.1 poly(rC)-binding protein 3 isoform X3

Conserved Domains (2) summary

cd00105
Location:298 → 360

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_006513916.4 → XP_006513979.1 poly(rC)-binding protein 3 isoform X1

See identical proteins and their annotated locations for XP_006513979.1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_030245199.1 → XP_030101059.1 poly(rC)-binding protein 3 isoform X12

Conserved Domains (3) summary

cd22519
Location:93 → 171

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:233 → 307

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cl00098
Location:6 → 82

KH-I; K homology (KH) RNA-binding domain, type I
XM_030245196.2 → XP_030101056.1 poly(rC)-binding protein 3 isoform X8

Conserved Domains (4) summary

pfam03154
Location:149 → 282

Atrophin-1; Atrophin-1 family

cd22516
Location:6 → 82

KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22519
Location:93 → 171

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:276 → 350

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
XM_011243517.4 → XP_011241819.1 poly(rC)-binding protein 3 isoform X7

See identical proteins and their annotated locations for XP_011241819.1

Conserved Domains (4) summary

pfam03154
Location:149 → 283

Atrophin-1; Atrophin-1 family

cd22516
Location:6 → 82

KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22519
Location:93 → 171

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:277 → 351

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
XM_036155904.1 → XP_036011797.1 poly(rC)-binding protein 3 isoform X2

Conserved Domains (4) summary

pfam03154
Location:181 → 314

Atrophin-1; Atrophin-1 family

cd22516
Location:38 → 114

KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:308 → 382

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
XM_006513919.5 → XP_006513982.1 poly(rC)-binding protein 3 isoform X1

See identical proteins and their annotated locations for XP_006513982.1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_011243516.4 → XP_011241818.1 poly(rC)-binding protein 3 isoform X1

See identical proteins and their annotated locations for XP_011241818.1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_030245192.2 → XP_030101052.1 poly(rC)-binding protein 3 isoform X2

Conserved Domains (4) summary

pfam03154
Location:181 → 314

Atrophin-1; Atrophin-1 family

cd22516
Location:38 → 114

KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:308 → 382

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
XM_030245190.2 → XP_030101050.1 poly(rC)-binding protein 3 isoform X1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_030245198.2 → XP_030101058.1 poly(rC)-binding protein 3 isoform X11

Conserved Domains (3) summary

cd22519
Location:93 → 171

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:254 → 328

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cl00098
Location:6 → 82

KH-I; K homology (KH) RNA-binding domain, type I
XM_030245195.2 → XP_030101055.1 poly(rC)-binding protein 3 isoform X6

Related

ENSMUSP00000101051.3, ENSMUST00000105411.9

Conserved Domains (2) summary

cd00105
Location:294 → 356

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_030245197.2 → XP_030101057.1 poly(rC)-binding protein 3 isoform X9

Conserved Domains (2) summary

cd00105
Location:275 → 337

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_036155906.1 → XP_036011799.1 poly(rC)-binding protein 3 isoform X5

UniProtKB/Swiss-Prot

P57722, Q8BSB0, Q8C544

Conserved Domains (3) summary

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:286 → 360

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cl00098
Location:38 → 114

KH-I; K homology (KH) RNA-binding domain, type I
XM_030245193.2 → XP_030101053.1 poly(rC)-binding protein 3 isoform X5

UniProtKB/Swiss-Prot

P57722, Q8BSB0, Q8C544

Conserved Domains (3) summary

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:286 → 360

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cl00098
Location:38 → 114

KH-I; K homology (KH) RNA-binding domain, type I
XM_036155905.1 → XP_036011798.1 poly(rC)-binding protein 3 isoform X5

UniProtKB/Swiss-Prot

P57722, Q8BSB0, Q8C544

Conserved Domains (3) summary

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:286 → 360

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cl00098
Location:38 → 114

KH-I; K homology (KH) RNA-binding domain, type I
XM_030245194.2 → XP_030101054.1 poly(rC)-binding protein 3 isoform X6

Conserved Domains (2) summary

cd00105
Location:294 → 356

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_006513917.1 → XP_006513980.1 poly(rC)-binding protein 3 isoform X1

See identical proteins and their annotated locations for XP_006513980.1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_006513918.1 → XP_006513981.1 poly(rC)-binding protein 3 isoform X1

See identical proteins and their annotated locations for XP_006513981.1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_017314038.1 → XP_017169527.1 poly(rC)-binding protein 3 isoform X5

UniProtKB/Swiss-Prot

P57722, Q8BSB0, Q8C544

Related

ENSMUSP00000129465.3, ENSMUST00000168465.9

Conserved Domains (3) summary

cd22519
Location:125 → 203

KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cd22522
Location:286 → 360

KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

cl00098
Location:38 → 114

KH-I; K homology (KH) RNA-binding domain, type I
XM_017314037.1 → XP_017169526.1 poly(rC)-binding protein 3 isoform X1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
XM_017314036.2 → XP_017169525.1 poly(rC)-binding protein 3 isoform X1

Conserved Domains (2) summary

cd00105
Location:318 → 380

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd02396
Location:131 → 195

PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...