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    Zfp707 zinc finger protein 707 [ Mus musculus (house mouse) ]

    Gene ID: 69020, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Zfp707provided by MGI
    Official Full Name
    zinc finger protein 707provided by MGI
    Primary source
    MGI:MGI:1916270
    See related
    Ensembl:ENSMUSG00000034429 AllianceGenome:MGI:1916270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500031N24Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in pancreas epithelium. Orthologous to human ZNF707 (zinc finger protein 707). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver adult (RPKM 12.1), colon adult (RPKM 10.5) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    15 D3; 15 35.17 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (75840972..75847717)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (75969123..75975868)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39034 Neighboring gene predicted gene, 53898 Neighboring gene eukaryotic translation initiation factor 2, subunit 3, pseudogene 1 Neighboring gene coiled-coil domain containing 166 Neighboring gene mitogen-activated protein kinase 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Mu X, et al. Nucleic Acids Res, 2001 Dec 15. PMID 11812828, Free PMC Article
    2. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 707

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081065.2 → NP_001074534.1  zinc finger protein 707 isoform 1

      See identical proteins and their annotated locations for NP_001074534.1

      Status: VALIDATED

      Source sequence(s)
      AC116487
      Consensus CDS
      CCDS37110.1
      UniProtKB/TrEMBL
      Q8R0U9
      Related
      ENSMUSP00000105593.4, ENSMUST00000109967.10
      Conserved Domains (5) summary
      smart00349
      Location:4 → 53
      KRAB; krueppel associated box
      COG5048
      Location:123 → 302
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:229 → 249
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 29
      KRAB; KRAB box
      pfam13465
      Location:241 → 266
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001347040.2 → NP_001333969.1  zinc finger protein 707 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC116487
      Consensus CDS
      CCDS84174.1
      UniProtKB/TrEMBL
      D3Z445
      Related
      ENSMUSP00000105592.2, ENSMUST00000109966.8

    3. NM_001361464.1 → NP_001348393.1  zinc finger protein 707 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC116487
      Related
      ENSMUSP00000119705.2, ENSMUST00000147641.8
      Conserved Domains (4) summary
      smart00349
      Location:49 → 109
      KRAB; krueppel associated box
      COG5048
      Location:179 → 358
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:285 → 305
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:367 → 389
      zf-C2H2; Zinc finger, C2H2 type

    4. NM_001361465.1 → NP_001348394.1  zinc finger protein 707 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AK137962, BU920097, CJ088003
      Conserved Domains (4) summary
      smart00349
      Location:26 → 86
      KRAB; krueppel associated box
      COG5048
      Location:156 → 335
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:262 → 282
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:344 → 366
      zf-C2H2; Zinc finger, C2H2 type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      75840972..75847717
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521341.4 → XP_006521404.1  zinc finger protein 707 isoform X1

      Conserved Domains (4) summary
      smart00349
      Location:48 → 108
      KRAB; krueppel associated box
      COG5048
      Location:178 → 357
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:284 → 304
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:366 → 388
      zf-C2H2; Zinc finger, C2H2 type
    Nucleotide Protein Strain
    Heading Accession and Version

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