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    Fam187b family with sequence similarity 187, member B [ Mus musculus (house mouse) ]

    Gene ID: 76415, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam187bprovided by MGI
    Official Full Name
    family with sequence similarity 187, member Bprovided by MGI
    Primary source
    MGI:MGI:1923665
    See related
    Ensembl:ENSMUSG00000046826 AllianceGenome:MGI:1923665
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tmem162; 1700020B09Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human FAM187B (family with sequence similarity 187 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 100.7) and large intestine adult (RPKM 2.3) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 B1; 7 19.28 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30673219..30689151)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30973794..30989726)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene upstream transcription factor 2 Neighboring gene lipolysis stimulated lipoprotein receptor Neighboring gene STARR-positive B cell enhancer ABC_E10435 Neighboring gene olfactory receptor 1359 pseudogene Neighboring gene predicted gene, 42377 Neighboring gene STARR-positive B cell enhancer ABC_E3713 Neighboring gene FXYD domain-containing ion transport regulator 5 Neighboring gene predicted gene, 38984 Neighboring gene microRNA 7050

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Gu Z, et al. PLoS One, 2015. PMID 25826454, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC159263

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM187B
    Names
    transmembrane protein 162

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001242647.2 → NP_001229576.2  protein FAM187B isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 5' terminal exon, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC149055
      UniProtKB/TrEMBL
      A0A0J9YV03
      Related
      ENSMUSP00000144424.2, ENSMUST00000128384.3

    2. NM_001377035.1 → NP_001363964.1  protein FAM187B isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC149055

    3. NM_001377036.1 → NP_001363965.1  protein FAM187B isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC149055
      Related
      ENSMUSP00000144533.2, ENSMUST00000129773.2

    4. NM_175240.5 → NP_780449.2  protein FAM187B isoform 1 precursor

      See identical proteins and their annotated locations for NP_780449.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC149055
      Consensus CDS
      CCDS21120.1
      UniProtKB/Swiss-Prot
      Q0VAY3, Q3UFH7
      Related
      ENSMUSP00000057020.5, ENSMUST00000058093.6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      30673219..30689151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153539.1 → XP_036009432.1  protein FAM187B isoform X1

    2. XM_036153540.1 → XP_036009433.1  protein FAM187B isoform X1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_019236.1: Suppressed sequence

      Description
      NG_019236.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VAY3.1 GenPept UniProtKB/Swiss-Prot:Q0VAY3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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