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    Fbxo28 F-box protein 28 [ Mus musculus (house mouse) ]

    Gene ID: 67948, updated on 5-Mar-2024

    Summary

    Official Symbol
    Fbxo28provided by MGI
    Official Full Name
    F-box protein 28provided by MGI
    Primary source
    MGI:MGI:1261890
    See related
    Ensembl:ENSMUSG00000047539 AllianceGenome:MGI:1261890
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fbx28; mKIAA0483; D1Ertd578e; 4833428J17Rik; 5730505P19Rik
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in kinetochore. Orthologous to human FBXO28 (F-box protein 28). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 7.0), CNS E14 (RPKM 6.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Fbxo28 in Genome Data Viewer
    Location:
    1 H5; 1 84.93 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (182140667..182169171, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (182313102..182341606, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene delta 4-desaturase, sphingolipid 1 Neighboring gene RIKEN cDNA 1700047M11 gene Neighboring gene STARR-seq mESC enhancer starr_03278 Neighboring gene STARR-positive B cell enhancer mm9_chr1:184271643-184271944 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E5879 Neighboring gene transformation related protein 53 binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA0483, MGC90899

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175127.2NP_780336.1  F-box only protein 28

      See identical proteins and their annotated locations for NP_780336.1

      Status: VALIDATED

      Source sequence(s)
      BC094542
      Consensus CDS
      CCDS15588.1
      UniProtKB/Swiss-Prot
      Q3TS97, Q7TMH9, Q8BIF6, Q8BIG4
      Related
      ENSMUSP00000054718.5, ENSMUST00000051431.10
      Conserved Domains (1) summary
      pfam00646
      Location:67108
      F-box; F-box domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      182140667..182169171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)