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    Aldoart1 aldolase 1 A, retrogene 1 [ Mus musculus (house mouse) ]

    Gene ID: 353204, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Aldoart1provided by MGI
    Official Full Name
    aldolase 1 A, retrogene 1provided by MGI
    Primary source
    MGI:MGI:2447811
    See related
    Ensembl:ENSMUSG00000059343 AllianceGenome:MGI:2447811
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Aldo1-ps; Aldo1-ps2; Aldoa-ps2; 4921524E03Rik
    Summary
    Predicted to enable several functions, including fructose binding activity; fructose-bisphosphate aldolase activity; and identical protein binding activity. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; fructose 1,6-bisphosphate metabolic process; and purine ribonucleotide metabolic process. Located in sperm fibrous sheath. Orthologous to human ALDOA (aldolase, fructose-bisphosphate A). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See Aldoart1 in Genome Data Viewer
    Location:
    4 C3; 4 36.06 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (72768820..72770871, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (72850583..72852634, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10525 Neighboring gene predicted gene 11232 Neighboring gene STARR-seq mESC enhancer starr_10526 Neighboring gene STARR-seq mESC enhancer starr_10527 Neighboring gene STARR-seq mESC enhancer starr_10528 Neighboring gene RIKEN cDNA C630043F03 gene Neighboring gene STARR-positive B cell enhancer ABC_E2695 Neighboring gene transducin-like enhancer of split 1 Neighboring gene STARR-seq mESC enhancer starr_10529 Neighboring gene STARR-seq mESC enhancer starr_10530 Neighboring gene STARR-seq mESC enhancer starr_10531 Neighboring gene STARR-seq mESC enhancer starr_10532 Neighboring gene STARR-seq mESC enhancer starr_10533 Neighboring gene STARR-seq mESC enhancer starr_10534 Neighboring gene predicted gene, 25653 Neighboring gene pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of Aldolase A pseudogenes in mice: multiple origins, subsequent duplications, and heterogeneity of evolutionary rates. Cortinas MN, et al. Mol Biol Evol, 2001 Sep. PMID 11504845
    2. Three male germline-specific aldolase A isozymes are generated by alternative splicing and retrotransposition. Vemuganti SA, et al. Dev Biol, 2007 Sep 1. PMID 17659271
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables fructose-bisphosphate aldolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fructose 1,6-bisphosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycolytic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in sperm fibrous sheath IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aldolase 1 A retrogene 1
    Names
    aldolase A retroprotein 1
    NP_001186199.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199270.1 → NP_001186199.1  aldolase 1 A retrogene 1

      See identical proteins and their annotated locations for NP_001186199.1

      Status: VALIDATED

      Source sequence(s)
      AL928642
      Consensus CDS
      CCDS57279.1
      UniProtKB/TrEMBL
      A6ZI46, Q9CPQ9
      Related
      ENSMUSP00000077687.5, ENSMUST00000078617.5
      Conserved Domains (1) summary
      pfam00274
      Location:70 → 419
      Glycolytic; Fructose-bisphosphate aldolase class-I

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      72768820..72770871 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_181346.2: Suppressed sequence

      Description
      NM_181346.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

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