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    Zbtb8os zinc finger and BTB domain containing 8 opposite strand [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297885, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Zbtb8osprovided by RGD
    Official Full Name
    zinc finger and BTB domain containing 8 opposite strandprovided by RGD
    Primary source
    RGD:1562249
    See related
    Ensembl:ENSRNOG00000008226 AllianceGenome:RGD:1562249
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562249; Zbtb8os-ps1
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be part of tRNA-splicing ligase complex. Orthologous to human ZBTB8OS (zinc finger and BTB domain containing 8 opposite strand). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 244.2), Adrenal (RPKM 168.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    5q36
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (146959939..146971389)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (141675595..141687148)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (147535584..147547252)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL23-like Neighboring gene syncoilin, intermediate filament protein Neighboring gene RB binding protein 4, chromatin remodeling factor Neighboring gene uncharacterized LOC120103131 Neighboring gene zinc finger and BTB domain containing 8a Neighboring gene small nucleolar RNA SNORA70

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors. Popow J, et al. Nature, 2014 Jul 3. PMID 24870230, Free PMC Article
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA splicing, via endonucleolytic cleavage and ligation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA splicing, via endonucleolytic cleavage and ligation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of tRNA-splicing ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of tRNA-splicing ligase complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein archease
    Names
    zinc finger and BTB domain containing 8 opposite strand, pseudogene 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399489.1 → NP_001386418.1  protein archease isoform 1

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      M0R5Y9
      Related
      ENSRNOP00000064823.1, ENSRNOT00000074628.4
      Conserved Domains (1) summary
      pfam01951
      Location:31 → 167
      Archease; Archease protein family (MTH1598/TM1083)

    2. NM_001399490.1 → NP_001386419.1  protein archease isoform 2

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6ISI4
      Conserved Domains (1) summary
      pfam01951
      Location:1 → 110
      Archease; Archease protein family (MTH1598/TM1083)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      146959939..146971389
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111528.2 → XP_038967456.1  protein archease isoform X1

      UniProtKB/TrEMBL
      A6ISI4
      Conserved Domains (1) summary
      pfam01951
      Location:1 → 110
      Archease; Archease protein family (MTH1598/TM1083)
    Nucleotide Protein Strain
    Heading Accession and Version

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