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    Mad2l1bp MAD2L1 binding protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316237, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mad2l1bpprovided by RGD
    Official Full Name
    MAD2L1 binding proteinprovided by RGD
    Primary source
    RGD:1309175
    See related
    Ensembl:ENSRNOG00000019463 AllianceGenome:RGD:1309175
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in deactivation of mitotic spindle assembly checkpoint and regulation of exit from mitosis. Predicted to be located in cytoplasm and nucleus. Predicted to be active in nucleus. Orthologous to human MAD2L1BP (MAD2L1 binding protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 50.5), Spleen (RPKM 49.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mad2l1bp in Genome Data Viewer
    Location:
    9q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (22329699..22334024)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (14832133..14836458)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (17217141..17221465)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene GTP binding protein 2 Neighboring gene ribosomal protein S2, pseudogene 6 Neighboring gene radial spoke head component 9 Neighboring gene mitochondrial ribosomal protein S18A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC109107

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in deactivation of mitotic spindle assembly checkpoint ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009699.1NP_001009699.1  MAD2L1-binding protein

      See identical proteins and their annotated locations for NP_001009699.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088268
      UniProtKB/TrEMBL
      A6JIT6, F7FQE7, Q5I0J2
      Related
      ENSRNOP00000026331.4, ENSRNOT00000026331.7
      Conserved Domains (1) summary
      pfam06581
      Location:41277
      p31comet; Mad1 and Cdc20-bound-Mad2 binding

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      22329699..22334024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)