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    Timm8b translocase of inner mitochondrial membrane 8 homolog B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64372, updated on 5-Mar-2024

    Summary

    Official Symbol
    Timm8bprovided by RGD
    Official Full Name
    translocase of inner mitochondrial membrane 8 homolog Bprovided by RGD
    Primary source
    RGD:619840
    See related
    Ensembl:ENSRNOG00000009888 AllianceGenome:RGD:619840
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ddp2
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in protein transport. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Orthologous to human TIMM8B (translocase of inner mitochondrial membrane 8 homolog B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 1740.5), Muscle (RPKM 1543.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    8q23
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (59850737..59852117)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (50954350..50955730)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (55037750..55039130)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene interleukin 18 Neighboring gene testis expressed 12 Neighboring gene succinate dehydrogenase complex subunit D Neighboring gene NKAP domain containing 1 Neighboring gene PIH1 domain containing 2 Neighboring gene dihydrolipoamide S-acetyltransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitochondrial import inner membrane translocase subunit Tim8 B
    Names
    deafness dystonia protein 2 homolog
    small zinc finger-like protein DDP2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022541.2NP_071986.1  mitochondrial import inner membrane translocase subunit Tim8 B

      See identical proteins and their annotated locations for NP_071986.1

      Status: VALIDATED

      Source sequence(s)
      AF196315, CF977529
      UniProtKB/Swiss-Prot
      P62078
      UniProtKB/TrEMBL
      A6J4E1
      Related
      ENSRNOP00000013188.2, ENSRNOT00000013188.6
      Conserved Domains (1) summary
      pfam02953
      Location:1674
      zf-Tim10_DDP; Tim10/DDP family zinc finger

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      59850737..59852117
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)