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    Cd96 CD96 molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498079, updated on 5-Mar-2024

    Summary

    Official Symbol
    Cd96provided by RGD
    Official Full Name
    CD96 moleculeprovided by RGD
    Primary source
    RGD:1565249
    See related
    Ensembl:ENSRNOG00000023030 AllianceGenome:RGD:1565249
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cell-matrix adhesion and inflammatory response. Predicted to act upstream of or within negative regulation of interferon-gamma production; negative regulation of natural killer cell cytokine production; and response to lipopolysaccharide. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in C syndrome. Orthologous to human CD96 (CD96 molecule). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 65.2), Spleen (RPKM 36.7) and 5 other tissues See more
    Orthologs
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    Genomic context

    Location:
    11q21
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (68164926..68239266)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (54702290..54776618)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (57108757..57183855)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 30 Neighboring gene zinc finger, BED-type containing 2, pseudogene 1 Neighboring gene phosphatidylinositol-specific phospholipase C, X domain containing 2 Neighboring gene pleckstrin homology-like domain, family B, member 2 Neighboring gene uncharacterized LOC102552450

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General protein information

    Preferred Names
    T-cell surface protein tactile
    Names
    CD96 antigen
    cell surface antigen CD96
    t cell-activated increased late expression protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025032.1NP_001020203.1  T-cell surface protein tactile precursor

      See identical proteins and their annotated locations for NP_001020203.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091206
      UniProtKB/Swiss-Prot
      Q5BK49
      UniProtKB/TrEMBL
      A6IQW9
      Related
      ENSRNOP00000034871.5, ENSRNOT00000035485.8
      Conserved Domains (1) summary
      cl11960
      Location:40137
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      68164926..68239266
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270703.1XP_063126773.1  T-cell surface protein tactile isoform X1