Sun1 Sad1 and UNC84 domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Sun1provided by MGI
Official Full Name: Sad1 and UNC84 domain containing 1provided by MGI
Primary source: MGI:MGI:1924303
See related: Ensembl:ENSMUSG00000036817 AllianceGenome:MGI:1924303
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Unc84a; mKIAA0810; 4632417G13Rik; 5730434D03Rik
Summary: Enables lamin binding activity. Involved in centrosome localization; meiotic attachment of telomere to nuclear envelope; and nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration. Acts upstream of or within homologous chromosome pairing at meiosis. Located in acrosomal membrane and nuclear envelope. Is integral component of nuclear inner membrane. Is expressed in intercostal muscle; spermatocyte; and spermatozoon. Orthologous to human SUN1 (Sad1 and UNC84 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis adult (RPKM 24.4), bladder adult (RPKM 22.9) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 5 G2; 5 78.12 cM

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (139186313..139235594)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (139200564..139249839)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation.
Title: Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation.
The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.
Title: The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.
Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy.
Title: Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy.
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Title: The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells.
Title: SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells.
Comparison of the miRNA profiles between wildtype and SUN1 null myotubes identified a cluster of miRNAs encoded by a non-translated retrotransposon-like one antisense (Rtl1as) transcript that are decreased in the WT myoblasts due to SUN1 inhibition of Drosha
Title: The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.
Results provide evidence that SUN1 and KASH5 are essential factors in the regulation of meiotic resumption and spindle formation.
Title: Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes.
A cell-type-specific role for Sun1 and Sun2 in nucleokinesis during cerebellar development, is reported.
Title: Sun1 deficiency leads to cerebellar ataxia in mice.
ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.
Title: CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase.
our results clearly indicate that SUN1 and SUN2, at least partially, fulfill redundant meiotic functions
Title: Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.

Submit: New GeneRIF Correction See all GeneRIFs (23)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (6) 1 citation
Endonuclease-mediated (2) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

UniSTS:235349 (e-PCR)
- UniSTS:235349

NoName (e-PCR)
- UniSTS:235350

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables cytoskeleton-nuclear membrane anchor activity	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables lamin binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-membrane adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in centrosome localization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within homologous chromosome pairing at meiosis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within meiotic attachment of telomere to nuclear envelope	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiotic attachment of telomere to nuclear envelope	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within meiotic cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nuclear envelope organization	ISO Inferred from Sequence Orthology more info
involved_in nuclear matrix anchoring at nuclear membrane	ISO Inferred from Sequence Orthology more info
involved_in nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within spermatogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome, telomeric region	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
part_of meiotic nuclear membrane microtubule tethering complex	IBA Inferred from Biological aspect of Ancestor more info
part_of meiotic nuclear membrane microtubule tethering complex	ISO Inferred from Sequence Orthology more info
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in nuclear envelope	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear envelope	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with nuclear envelope	ISO Inferred from Sequence Orthology more info
located_in nuclear envelope	ISO Inferred from Sequence Orthology more info
located_in nuclear envelope	TAS Traceable Author Statement more info
located_in nuclear inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in nuclear membrane	ISO Inferred from Sequence Orthology more info
NOT located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: SUN domain-containing protein 1

Names: protein unc-84 homolog A; sad1/unc-84 protein-like 1; unc-84 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001256115.1 → NP_001243044.1 SUN domain-containing protein 1 isoform 2

See identical proteins and their annotated locations for NP_001243044.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.

Source sequence(s)

AK036187, AV239459, CK389844

Consensus CDS

CCDS57395.1

UniProtKB/Swiss-Prot

Q9D666

Related

ENSMUSP00000106508.3, ENSMUST00000110884.9

Conserved Domains (2) summary

pfam07738
Location:740 → 874

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:73 → 378

MRP; Mitochondrial RNA binding protein MRP
NM_001256116.2 → NP_001243045.1 SUN domain-containing protein 1 isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.

Source sequence(s)

AC125065

Consensus CDS

CCDS57396.1

UniProtKB/Swiss-Prot

Q9D666

Related

ENSMUSP00000077756.7, ENSMUST00000078690.13

Conserved Domains (2) summary

pfam07738
Location:713 → 847

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:73 → 351

MRP; Mitochondrial RNA binding protein MRP
NM_001256117.1 → NP_001243046.1 SUN domain-containing protein 1 isoform 4

See identical proteins and their annotated locations for NP_001243046.1

Status: VALIDATED

Description

Transcript Variant: This variant (4) lacks three consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) lacks an internal segment, compared to isoform 1.

Source sequence(s)

AK014585, AV239459, CK389844

Consensus CDS

CCDS57397.1

UniProtKB/Swiss-Prot

Q9D666

Related

ENSMUSP00000106507.3, ENSMUST00000110883.9

Conserved Domains (2) summary

pfam07738
Location:654 → 788

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:73 → 292

MRP; Mitochondrial RNA binding protein MRP
NM_001256118.1 → NP_001243047.1 SUN domain-containing protein 1 isoform 5

See identical proteins and their annotated locations for NP_001243047.1

Status: VALIDATED

Description

Transcript Variant: This variant (5) lacks four consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (5) lacks an internal segment, compared to isoform 1.

Source sequence(s)

AK160281, BQ551727, HQ402597

Consensus CDS

CCDS57398.1

UniProtKB/Swiss-Prot

Q9D666

Related

ENSMUSP00000106506.2, ENSMUST00000110882.8

Conserved Domains (2) summary

pfam07738
Location:621 → 755

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:73 → 259

MRP; Mitochondrial RNA binding protein MRP
NM_001359494.1 → NP_001346423.1 SUN domain-containing protein 1 isoform 6

Status: VALIDATED

Description

Transcript Variant: This variant (6) lacks an in-frame exon in the coding region and uses an alternate in-frame splice junction, compared to variant 1. The resulting isoform (6) is shorter than isoform 1.

Source sequence(s)

AC125065

Conserved Domains (3) summary

pfam07738
Location:712 → 846

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:73 → 351

MRP; Mitochondrial RNA binding protein MRP

cl25732
Location:428 → 579

SMC_N; RecF/RecN/SMC N terminal domain
NM_001359496.1 → NP_001346425.1 SUN domain-containing protein 1 isoform 7

Status: VALIDATED

Description

Transcript Variant: This variant (7) lacks two alternate in-frame exons, compared to variant 1. The resulting isoform (7) is shorter than isoform 1.

Source sequence(s)

AC125065

Conserved Domains (3) summary

pfam07738
Location:676 → 810

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:73 → 314

MRP; Mitochondrial RNA binding protein MRP

cl25732
Location:385 → 564

SMC_N; RecF/RecN/SMC N terminal domain
NM_024451.2 → NP_077771.1 SUN domain-containing protein 1 isoform 1

See identical proteins and their annotated locations for NP_077771.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1).

Source sequence(s)

AK160281, AK167686, BY036585

Consensus CDS

CCDS19804.1

UniProtKB/Swiss-Prot

D3Z0V9, Q3TIW3, Q3TV96, Q6B4H0, Q80SU8, Q8BZ99, Q99P23, Q9D666

Related

ENSMUSP00000056655.8, ENSMUST00000058716.14

Conserved Domains (5) summary

COG1196
Location:486 → 665

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam07738
Location:777 → 911

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:63 → 415

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:709 → 734

Sun2_CC2; SUN2 coiled coil domain 2

cd21439
Location:553 → 606

SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000071.7 Reference GRCm39 C57BL/6J

Range

139186313..139235594

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036165598.1 → XP_036021491.1 SUN domain-containing protein 1 isoform X22

UniProtKB/TrEMBL

Q3TSM1

Related

ENSMUSP00000098086.4, ENSMUST00000100517.10

Conserved Domains (1) summary

pfam09387
Location:92 → 253

MRP; Mitochondrial RNA binding protein MRP
XM_017321156.3 → XP_017176645.1 SUN domain-containing protein 1 isoform X1

Conserved Domains (4) summary

pfam07738
Location:815 → 949

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:543 → 706

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 259

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:747 → 772

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321157.3 → XP_017176646.1 SUN domain-containing protein 1 isoform X2

Conserved Domains (4) summary

pfam07738
Location:814 → 948

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:543 → 705

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 259

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:746 → 771

Sun2_CC2; SUN2 coiled coil domain 2
XM_036165596.1 → XP_036021489.1 SUN domain-containing protein 1 isoform X8

Conserved Domains (4) summary

pfam07738
Location:777 → 911

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:92 → 416

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:709 → 734

Sun2_CC2; SUN2 coiled coil domain 2

cd21439
Location:554 → 605

SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins
XM_017321162.3 → XP_017176651.1 SUN domain-containing protein 1 isoform X6

Conserved Domains (4) summary

pfam07738
Location:778 → 912

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:506 → 669

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 416

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:710 → 735

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321164.3 → XP_017176653.1 SUN domain-containing protein 1 isoform X10

Conserved Domains (4) summary

pfam07738
Location:756 → 890

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:484 → 647

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 394

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:688 → 713

Sun2_CC2; SUN2 coiled coil domain 2
XM_030254889.2 → XP_030110749.1 SUN domain-containing protein 1 isoform X3

Conserved Domains (4) summary

pfam07738
Location:805 → 939

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:534 → 696

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 250

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:737 → 762

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321165.3 → XP_017176654.1 SUN domain-containing protein 1 isoform X11

Conserved Domains (4) summary

pfam07738
Location:751 → 885

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:479 → 642

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 389

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:683 → 708

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321168.3 → XP_017176657.1 SUN domain-containing protein 1 isoform X13

Conserved Domains (4) summary

pfam07738
Location:714 → 848

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:442 → 605

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 352

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:646 → 671

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321163.3 → XP_017176652.1 SUN domain-containing protein 1 isoform X9

Conserved Domains (4) summary

pfam07738
Location:768 → 902

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:497 → 659

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 407

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:700 → 725

Sun2_CC2; SUN2 coiled coil domain 2
XM_030254894.2 → XP_030110754.1 SUN domain-containing protein 1 isoform X16

Conserved Domains (4) summary

pfam07738
Location:691 → 825

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:420 → 582

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 330

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:623 → 648

Sun2_CC2; SUN2 coiled coil domain 2
XM_030254890.2 → XP_030110750.1 SUN domain-containing protein 1 isoform X12

Conserved Domains (4) summary

pfam07738
Location:747 → 881

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:475 → 638

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 385

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:679 → 704

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321170.3 → XP_017176659.1 SUN domain-containing protein 1 isoform X15

Conserved Domains (4) summary

pfam07738
Location:692 → 826

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:420 → 583

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 330

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:624 → 649

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321171.3 → XP_017176660.1 SUN domain-containing protein 1 isoform X18

Conserved Domains (4) summary

pfam07738
Location:659 → 793

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:387 → 550

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 297

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:591 → 616

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321169.3 → XP_017176658.1 SUN domain-containing protein 1 isoform X14

Conserved Domains (4) summary

pfam07738
Location:704 → 838

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:433 → 595

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 343

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:636 → 661

Sun2_CC2; SUN2 coiled coil domain 2
XM_036165597.1 → XP_036021490.1 SUN domain-containing protein 1 isoform X17

Conserved Domains (4) summary

pfam07738
Location:682 → 816

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:92 → 321

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:614 → 639

Sun2_CC2; SUN2 coiled coil domain 2

cd21439
Location:459 → 510

SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins
XM_006504767.4 → XP_006504830.1 SUN domain-containing protein 1 isoform X19

Conserved Domains (4) summary

pfam07738
Location:650 → 784

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:378 → 541

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:102 → 288

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:582 → 607

Sun2_CC2; SUN2 coiled coil domain 2
XM_036165595.1 → XP_036021488.1 SUN domain-containing protein 1 isoform X7

UniProtKB/Swiss-Prot

D3Z0V9, Q3TIW3, Q3TV96, Q6B4H0, Q80SU8, Q8BZ99, Q99P23, Q9D666

Conserved Domains (5) summary

COG1196
Location:486 → 665

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam07738
Location:777 → 911

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam09387
Location:63 → 415

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:709 → 734

Sun2_CC2; SUN2 coiled coil domain 2

cd21439
Location:553 → 606

SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins
XM_017321160.2 → XP_017176649.1 SUN domain-containing protein 1 isoform X5

Conserved Domains (4) summary

pfam07738
Location:786 → 920

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:514 → 677

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:73 → 230

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:718 → 743

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321159.2 → XP_017176648.1 SUN domain-containing protein 1 isoform X5

Conserved Domains (4) summary

pfam07738
Location:786 → 920

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:514 → 677

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:73 → 230

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:718 → 743

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321161.2 → XP_017176650.1 SUN domain-containing protein 1 isoform X5

Conserved Domains (4) summary

pfam07738
Location:786 → 920

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:514 → 677

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:73 → 230

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:718 → 743

Sun2_CC2; SUN2 coiled coil domain 2
XM_030254895.2 → XP_030110755.1 SUN domain-containing protein 1 isoform X20

Conserved Domains (4) summary

pfam07738
Location:629 → 763

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:358 → 520

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:82 → 268

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:561 → 586

Sun2_CC2; SUN2 coiled coil domain 2
XM_030254897.2 → XP_030110757.1 SUN domain-containing protein 1 isoform X21

Conserved Domains (4) summary

pfam07738
Location:620 → 754

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:349 → 511

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:73 → 259

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:552 → 577

Sun2_CC2; SUN2 coiled coil domain 2
XM_017321158.1 → XP_017176647.1 SUN domain-containing protein 1 isoform X4

Conserved Domains (4) summary

pfam07738
Location:795 → 929

Sad1_UNC; Sad1 / UNC-like C-terminal

pfam07888
Location:523 → 686

CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like

pfam09387
Location:82 → 239

MRP; Mitochondrial RNA binding protein MRP

pfam18580
Location:727 → 752

Sun2_CC2; SUN2 coiled coil domain 2