2210016L21Rik RIKEN cDNA 2210016L21 gene [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: 2210016L21Rikprovided by MGI
Official Full Name: RIKEN cDNA 2210016L21 geneprovided by MGI
Primary source: MGI:MGI:1919607
See related: Ensembl:ENSMUSG00000029559 AllianceGenome:MGI:1919607
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Custos
Summary: Predicted to be involved in Spemann organizer formation and negative regulation of Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in nucleus. Orthologous to human C12orf43 (chromosome 12 open reading frame 43). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in cerebellum adult (RPKM 29.9), cortex adult (RPKM 28.5) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 5 F; 5 55.99 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (115080213..115086610)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (114942154..114948540)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)

General gene information

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Markers

M57966 (e-PCR)
- UniSTS:124958

AI323641 (e-PCR)
- UniSTS:179245

Tcf1 (e-PCR), detects polymorphism
- UniSTS:144554

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in Spemann organizer formation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within multicellular organism development	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of Wnt signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein CUSTOS

Names: uncharacterized protein C12orf43 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.