Armt1 acidic residue methyltransferase 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Armt1provided by MGI
Official Full Name: acidic residue methyltransferase 1provided by MGI
Primary source: MGI:MGI:1920669
See related: Ensembl:ENSMUSG00000061759 AllianceGenome:MGI:1920669
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1700052N19Rik
Summary: Predicted to enable enzyme binding activity; methyltransferase activity; and phosphatase activity. Predicted to be involved in methylation and regulation of response to DNA damage stimulus. Predicted to act upstream of or within cellular response to DNA damage stimulus. Orthologous to human ARMT1 (acidic residue methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis adult (RPKM 19.5), liver E14 (RPKM 6.3) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 A1; 10 2.06 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (4382572..4405140)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (4429275..4455140)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)
Endonuclease-mediated (2)

General gene information

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Markers

AW320013 (e-PCR)
- UniSTS:180006

px-31f3 (e-PCR)
- UniSTS:257585

NoName (e-PCR)
- UniSTS:237898

UniSTS:495977 (e-PCR)
- UniSTS:495977

Avpr1b (e-PCR), detects polymorphism
- UniSTS:495977

px-38e3 (e-PCR)
- UniSTS:257695

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables S-adenosylmethionine-dependent methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein carboxyl O-methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA damage response	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA damage response	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: damage-control phosphatase ARMT1

Names: UPF0364 protein C6orf211 homolog; protein-glutamate O-methyltransferase; sugar phosphate phosphatase ARMT1

NP_077223.2

EC 2.1.1.-

EC 3.1.3.-

XP_011241402.1

EC 2.1.1.-

EC 3.1.3.-

XP_011241403.1

EC 2.1.1.-

EC 3.1.3.-

XP_030101175.1

EC 2.1.1.-

EC 3.1.3.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_024261.2 → NP_077223.2 damage-control phosphatase ARMT1

See identical proteins and their annotated locations for NP_077223.2

Status: VALIDATED

Source sequence(s)

BC099894, BU148062

Consensus CDS

CCDS56676.1

UniProtKB/Swiss-Prot

A6H630, Q499H1, Q99M05, Q9D9L4

Related

ENSMUSP00000093581.5, ENSMUST00000095893.11

Conserved Domains (1) summary

pfam01937
Location:20 → 417

DUF89; Protein of unknown function DUF89

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000076.7 Reference GRCm39 C57BL/6J

Range

4382572..4405140

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011243100.4 → XP_011241402.1 damage-control phosphatase ARMT1 isoform X1

See identical proteins and their annotated locations for XP_011241402.1

Conserved Domains (1) summary

pfam01937
Location:50 → 331

DUF89; Protein of unknown function DUF89
XM_030245315.2 → XP_030101175.1 damage-control phosphatase ARMT1 isoform X2

Conserved Domains (1) summary

pfam01937
Location:1 → 298

DUF89; Protein of unknown function DUF89
XM_011243101.4 → XP_011241403.1 damage-control phosphatase ARMT1 isoform X1

See identical proteins and their annotated locations for XP_011241403.1

Conserved Domains (1) summary

pfam01937
Location:50 → 331

DUF89; Protein of unknown function DUF89