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    Dip2c disco interacting protein 2 homolog C [ Mus musculus (house mouse) ]

    Gene ID: 208440, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Dip2cprovided by MGI
    Official Full Name
    disco interacting protein 2 homolog Cprovided by MGI
    Primary source
    MGI:MGI:1920179
    See related
    Ensembl:ENSMUSG00000048264 AllianceGenome:MGI:1920179
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0934; 9630044M06; 2900024P20Rik
    Summary
    Orthologous to human DIP2C (disco interacting protein 2 homolog C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 8.8), whole brain E14.5 (RPKM 7.1) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    13 A1; 13 3.7 cM
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (9326530..9718964)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (9276507..9668928)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_33614 Neighboring gene STARR-seq mESC enhancer starr_33615 Neighboring gene predicted gene 8784 Neighboring gene STARR-seq mESC enhancer starr_33616 Neighboring gene predicted gene, 46391 Neighboring gene eukaryotic translation initiation factor 4E nuclear import factor 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_33619 Neighboring gene STARR-seq mESC enhancer starr_33622 Neighboring gene STARR-seq mESC enhancer starr_33624 Neighboring gene STARR-seq mESC enhancer starr_33625 Neighboring gene predicted gene, 36423 Neighboring gene zinc finger, MYND domain containing 11 Neighboring gene STARR-positive B cell enhancer ABC_E4050 Neighboring gene STARR-positive B cell enhancer ABC_E1454 Neighboring gene predicted gene, 40665

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. Ma J, et al. PLoS Biol, 2019 Oct. PMID 31600191, Free PMC Article
    2. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
    3. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (4)  1 citation

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0934

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    disco-interacting protein 2 homolog C
    Names
    DIP2 disco-interacting protein 2 homolog C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081426.2 → NP_001074895.2  disco-interacting protein 2 homolog C

      See identical proteins and their annotated locations for NP_001074895.2

      Status: VALIDATED

      Source sequence(s)
      AC124579, AC131743, AC133934
      Consensus CDS
      CCDS36589.2
      UniProtKB/TrEMBL
      B2RQ71, E9PWR4
      Related
      ENSMUSP00000133806.2, ENSMUST00000174552.8
      Conserved Domains (2) summary
      cd05905
      Location:988 → 1552
      Dip2; Disco-interacting protein 2 (Dip2)
      pfam06464
      Location:8 → 118
      DMAP_binding; DMAP1-binding Domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      9326530..9718964
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516475.5 → XP_006516538.1  disco-interacting protein 2 homolog C isoform X3

      UniProtKB/TrEMBL
      E9PWR4
      Conserved Domains (2) summary
      cd05905
      Location:992 → 1556
      Dip2; Disco-interacting protein 2 (Dip2)
      pfam06464
      Location:8 → 118
      DMAP_binding; DMAP1-binding Domain

    2. XM_006516473.3 → XP_006516536.1  disco-interacting protein 2 homolog C isoform X1

      UniProtKB/TrEMBL
      E9PWR4
      Conserved Domains (2) summary
      cd05905
      Location:1048 → 1612
      Dip2; Disco-interacting protein 2 (Dip2)
      pfam06464
      Location:8 → 174
      DMAP_binding; DMAP1-binding Domain

    3. XM_006516474.4 → XP_006516537.1  disco-interacting protein 2 homolog C isoform X2

      UniProtKB/TrEMBL
      E9PWR4
      Related
      ENSMUSP00000131238.3, ENSMUST00000169960.10
      Conserved Domains (2) summary
      cd05905
      Location:1044 → 1608
      Dip2; Disco-interacting protein 2 (Dip2)
      pfam06464
      Location:8 → 174
      DMAP_binding; DMAP1-binding Domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_172459.1: Suppressed sequence

      Description
      NM_172459.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
    Nucleotide Protein Strain
    Heading Accession and Version

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