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    Utp14a UTP14A small subunit processome component [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317579, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Utp14aprovided by RGD
    Official Full Name
    UTP14A small subunit processome componentprovided by RGD
    Primary source
    RGD:1359313
    See related
    Ensembl:ENSRNOG00000005012 AllianceGenome:RGD:1359313
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in rRNA processing. Predicted to be located in cytosol. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP14A (UTP14A small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 58.6), Thymus (RPKM 57.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    Xq36
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (132317163..132342524)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (127439282..127464634)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (135092123..135117409)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 9 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene BCL6 co-repressor-like 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit B4, pseudogene 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    U3 small nucleolar RNA-associated protein 14 homolog A
    Names
    UTP14, U3 small nucleolar ribonucleoprotein, homolog A
    UTP14A small subunit (SSU) processome component

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014113.2 → NP_001014135.2  U3 small nucleolar RNA-associated protein 14 homolog A

      See identical proteins and their annotated locations for NP_001014135.2

      Status: PROVISIONAL

      Source sequence(s)
      BC099799
      UniProtKB/TrEMBL
      A0A8I5ZJ69, Q499R2
      Related
      ENSRNOP00000051553.5, ENSRNOT00000048022.6
      Conserved Domains (1) summary
      pfam04615
      Location:29 → 728
      Utp14; Utp14 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      132317163..132342524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099850.2 → XP_038955778.2  U3 small nucleolar RNA-associated protein 14 homolog A isoform X1

    2. XM_039099849.2 → XP_038955777.1  U3 small nucleolar RNA-associated protein 14 homolog A isoform X2

      UniProtKB/TrEMBL
      A6JMP9
      Conserved Domains (1) summary
      pfam04615
      Location:96 → 573
      Utp14; Utp14 protein
    Nucleotide Protein Strain
    Heading Accession and Version

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