Exoc6 exocyst complex component 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Exoc6provided by RGD
Official Full Name: exocyst complex component 6provided by RGD
Primary source: RGD:3653
See related: Ensembl:ENSRNOG00000036601 AllianceGenome:RGD:3653
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Sec15; Sec15l1
Summary: Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to act upstream of or within erythrocyte differentiation. Predicted to be located in Flemming body; growth cone; and perinuclear region of cytoplasm. Predicted to be part of exocyst. Orthologous to human EXOC6 (exocyst complex component 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 139.7), Spleen (RPKM 93.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q53

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (244727084..244870263)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (235314612..235457824)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (256211879..256369318)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AU049881 (e-PCR)
- UniSTS:146326

AU025595 (e-PCR)
- UniSTS:115107

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in Golgi to plasma membrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within erythrocyte differentiation	ISO Inferred from Sequence Orthology more info
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle tethering involved in exocytosis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Flemming body	IEA Inferred from Electronic Annotation more info
part_of exocyst	IBA Inferred from Biological aspect of Ancestor more info
part_of exocyst	IEA Inferred from Electronic Annotation more info
located_in growth cone	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: exocyst complex component 6

Names: SEC15-like 1; SEC15-like protein 1; exocyst complex component Sec15A; rSec15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_019277.2 → NP_062150.2 exocyst complex component 6

See identical proteins and their annotated locations for NP_062150.2

Status: VALIDATED

Source sequence(s)

AF032668

UniProtKB/Swiss-Prot

O54923

UniProtKB/TrEMBL

A6I171, F1M0F4

Related

ENSRNOP00000051630.3, ENSRNOT00000054748.5

Conserved Domains (1) summary

pfam04091
Location:456 → 762

Sec15; Exocyst complex subunit Sec15-like

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

244727084..244870263

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039088459.2 → XP_038944387.1 exocyst complex component 6 isoform X1

UniProtKB/TrEMBL

A6I171, F1M0F4

Conserved Domains (1) summary

pfam04091
Location:307 → 613

Sec15; Exocyst complex subunit Sec15-like