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    Gpr153 G protein-coupled receptor 153 [ Mus musculus (house mouse) ]

    Gene ID: 100129, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Gpr153provided by MGI
    Official Full Name
    G protein-coupled receptor 153provided by MGI
    Primary source
    MGI:MGI:1916157
    See related
    Ensembl:ENSMUSG00000042804 AllianceGenome:MGI:1916157
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PGR1; 1110065N12Rik
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including craniocervical region bone; esophagus; heart valve; neural retina; and submandibular gland primordium mesenchyme. Orthologous to human GPR153 (G protein-coupled receptor 153). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in ovary adult (RPKM 45.3), mammary gland adult (RPKM 24.8) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Gpr153 in Genome Data Viewer
    Location:
    4 E2; 4 83.0 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (152358563..152369798)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (152274106..152285342)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12198 Neighboring gene predicted gene, 30622 Neighboring gene STARR-positive B cell enhancer ABC_E6292 Neighboring gene acyl-CoA thioesterase 7 Neighboring gene STARR-seq mESC enhancer starr_12200 Neighboring gene STARR-positive B cell enhancer ABC_E9627 Neighboring gene STARR-positive B cell enhancer ABC_E4736 Neighboring gene STARR-positive B cell enhancer ABC_E3558 Neighboring gene hes family bHLH transcription factor 3 Neighboring gene isoprenylcysteine carboxyl methyltransferase Neighboring gene RIKEN cDNA 9430083M05 gene Neighboring gene ring finger protein 207 Neighboring gene ribosomal protein L22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The G protein-coupled receptor repertoires of human and mouse. Vassilatis DK, et al. Proc Natl Acad Sci U S A, 2003 Apr 15. PMID 12679517, Free PMC Article
    2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable G-protein coupled receptor 153
    Names
    G protein-coupled receptor PGR1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374784.1 → NP_001361713.1  probable G-protein coupled receptor 153 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL611985
      Consensus CDS
      CCDS89864.1
      UniProtKB/TrEMBL
      A2A8K5
      Related
      ENSMUSP00000101275.2, ENSMUST00000105650.8
      Conserved Domains (2) summary
      cd14964
      Location:9 → 35
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:8 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. NM_178406.2 → NP_848493.1  probable G-protein coupled receptor 153 isoform 1

      See identical proteins and their annotated locations for NP_848493.1

      Status: VALIDATED

      Source sequence(s)
      AL611985
      Consensus CDS
      CCDS18996.1
      UniProtKB/Swiss-Prot
      Q80T37, Q8CFK0, Q8K0Z9
      Related
      ENSMUSP00000101276.2, ENSMUST00000105651.8
      Conserved Domains (3) summary
      PHA03247
      Location:359 → 587
      PHA03247; large tegument protein UL36; Provisional
      cd14964
      Location:10 → 34
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:8 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      152358563..152369798
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250170.3 → XP_011248472.1  probable G-protein coupled receptor 153 isoform X1

      Conserved Domains (3) summary
      PHA03247
      Location:299 → 527
      PHA03247; large tegument protein UL36; Provisional
      cd14964
      Location:9 → 35
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:8 → 248
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8K0Z9.2 GenPept UniProtKB/Swiss-Prot:Q8K0Z9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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