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Hmga1 high mobility group AT-hook 1 [ Mus musculus (house mouse) ]

Gene ID: 15361, updated on 21-Apr-2024

Summary

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Official Symbol: Hmga1provided by MGI
Official Full Name: high mobility group AT-hook 1provided by MGI
Primary source: MGI:MGI:96160
See related: Ensembl:ENSMUSG00000046711 AllianceGenome:MGI:96160
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Hmgi; Hmgy; Hmgiy; Hmga1a; Hmga1b
Summary: This locus encodes a member of the nuclear, non-histone high mobility group protein family. This architectural transcription factor binds to A-T rich DNA sequences and participates in enhanceosome formation, chromatin remodeling and regulation of transcription. This protein functions in many cellular processes, including cell growth and differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Expression: Ubiquitous expression in thymus adult (RPKM 119.5), liver E14.5 (RPKM 82.7) and 27 other tissues See more
Orthologs: human all
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Genomic context

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Location:: 17 A3.3; 17 14.5 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (27774798..27782649)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (27556574..27563672)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
Title: HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Title: High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Asymmetric expression of maternal mRNA governs first cell-fate decision.
Title: Asymmetric expression of maternal mRNA governs first cell-fate decision.
High-mobility group AT-hook 1 promotes cardiac dysfunction in diabetic cardiomyopathy via autophagy inhibition.
Title: High-mobility group AT-hook 1 promotes cardiac dysfunction in diabetic cardiomyopathy via autophagy inhibition.
HMGA1-pseudogene7 transgenic mice develop B cell lymphomas.
Title: HMGA1-pseudogene7 transgenic mice develop B cell lymphomas.
Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice.
Title: Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice.
findings highlight a novel FoxO1/HMGA1-mediated mechanism by which insulin may regulate gene expression and metabolism.
Title: Cross-talk among HMGA1 and FoxO1 in control of nuclear insulin signaling.
HMGA1 expression was closely correlated with the clinical stage, histological grade, and tumor size in breast cancer patients and breast cancer progression in transgenic MMTV-PyMT mice
Title: HMGA1 Overexpression is Associated With the Malignant Status and Progression of Breast Cancer.
Results define a unique role for Hmga1 in intestinal homeostasis by maintaining the stem cell pool and fostering terminal differentiation to establish an epithelial stem cell niche.
Title: HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.
Forced expression of HMGA1 in primary cultured hepatocytes from Hmga1 (-/-) mice increased FoxO1 mRNA and protein levels.
Title: HMGA1 is a novel transcriptional regulator of the FoxO1 gene.

Submit: New GeneRIF Correction See all GeneRIFs (40)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (7) 1 citation
Endonuclease-mediated (5)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

PMC109291P1 (e-PCR)
- UniSTS:270161

RH125451 (e-PCR)
- UniSTS:162270

AI413582 (e-PCR)
- UniSTS:180967

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables 5'-deoxyribose-5-phosphate lyase activity	ISO Inferred from Sequence Orthology more info
enables D-loop DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	ISO Inferred from Sequence Orthology more info
enables DNA binding, bending	ISO Inferred from Sequence Orthology more info
enables DNA-(apurinic or apyrimidinic site) endonuclease activity	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA polymerase II core promoter sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables chromatin binding	IDA Inferred from Direct Assay more info	PubMed
enables cis-regulatory region sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info
enables minor groove of adenine-thymine-rich DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables minor groove of adenine-thymine-rich DNA binding	ISO Inferred from Sequence Orthology more info
enables molecular adaptor activity	ISO Inferred from Sequence Orthology more info
enables molecular function activator activity	ISO Inferred from Sequence Orthology more info
enables nuclear receptor coactivator activity	ISO Inferred from Sequence Orthology more info
enables nuclear retinoic acid receptor binding	ISO Inferred from Sequence Orthology more info
enables nuclear retinoid X receptor binding	ISO Inferred from Sequence Orthology more info
enables peroxisome proliferator activated receptor binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables structural constituent of chromatin	TAS Traceable Author Statement more info	PubMed
enables transcription coactivator activity	IDA Inferred from Direct Assay more info	PubMed
enables transcription coactivator activity	ISO Inferred from Sequence Orthology more info
enables transcription coregulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coregulator binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within B cell differentiation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within T cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within autophagy	IDA Inferred from Direct Assay more info	PubMed
involved_in base-excision repair	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within cell population proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within chromatin organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within erythrocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within gene expression	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within gene expression	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within glucose homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within heart development	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within heart development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within inflammatory cell apoptotic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within inflammatory response	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within insulin receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within insulin receptor signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within insulin receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within insulin secretion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lung morphogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within lymphoid progenitor cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within multicellular organism growth	IGI Inferred from Genetic Interaction more info	PubMed
involved_in negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of cell population proliferation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within neurogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in oncogene-induced cell senescence	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within peroxisome proliferator activated receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within respiratory system process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to cAMP	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to glucagon	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to glucose	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to insulin	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to insulin	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to insulin	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to wounding	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within thyroid gland development	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
part_of RNA polymerase II transcription regulator complex	IDA Inferred from Direct Assay more info	PubMed
part_of SUMO ligase complex	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in male germ cell nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IPI Inferred from Physical Interaction more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of senescence-associated heterochromatin focus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: high mobility group protein HMG-I/HMG-Y

Names: high mobility group AT-hook protein 1; high mobility group protein A1; high mobility group protein I

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025427.3 → NP_001020598.1 high mobility group protein HMG-I/HMG-Y isoform a

See identical proteins and their annotated locations for NP_001020598.1

Status: REVIEWED

Description

Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 through 5 encode the same isoform (a), also known as isoform I.

Source sequence(s)

AK171334, AV018894, BY270784

Consensus CDS

CCDS28564.1

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0

Related

ENSMUSP00000156173.2, ENSMUST00000232265.2
NM_001039356.2 → NP_001034445.1 high mobility group protein HMG-I/HMG-Y isoform a

See identical proteins and their annotated locations for NP_001034445.1

Status: REVIEWED

Description

Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 through 5 encode the same isoform (a), also known as isoform I.

Source sequence(s)

AK171334, AV018894, BY270784, GH454882

Consensus CDS

CCDS28564.1

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0

Related

ENSMUSP00000113015.2, ENSMUST00000118599.9

Conserved Domains (1) summary

pfam06217
Location:4 → 87

GAGA_bind; GAGA binding protein-like family
NM_001166535.1 → NP_001160007.1 high mobility group protein HMG-I/HMG-Y isoform a

See identical proteins and their annotated locations for NP_001160007.1

Status: REVIEWED

Description

Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 through 5 encode the same isoform (a), also known as isoform I.

Source sequence(s)

AK171334, AV018894, BY165675, BY270784

Consensus CDS

CCDS28564.1

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0

Related

ENSMUSP00000113916.2, ENSMUST00000119486.9

Conserved Domains (1) summary

pfam06217
Location:4 → 87

GAGA_bind; GAGA binding protein-like family
NM_001166536.1 → NP_001160008.1 high mobility group protein HMG-I/HMG-Y isoform a

See identical proteins and their annotated locations for NP_001160008.1

Status: REVIEWED

Description

Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1 through 5 encode the same isoform (a), also known as isoform I.

Source sequence(s)

AK171334, AV018894, BY270784

Consensus CDS

CCDS28564.1

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0

Related

ENSMUSP00000155886.2, ENSMUST00000232013.2

Conserved Domains (1) summary

pfam06217
Location:4 → 87

GAGA_bind; GAGA binding protein-like family
NM_001166537.1 → NP_001160009.1 high mobility group protein HMG-I/HMG-Y isoform b

See identical proteins and their annotated locations for NP_001160009.1

Status: REVIEWED

Description

Transcript Variant: This variant (6) uses an alternate, in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 6 through 10 encode the same isoform (b), also known as isoform Y.

Source sequence(s)

AK155661, AK171334, AV018894, BM937661, CF730372

Consensus CDS

CCDS50044.1

UniProtKB/TrEMBL

A0A338P6G6, Q3TVP0

Related

ENSMUSP00000114101.2, ENSMUST00000118570.2

Conserved Domains (1) summary

PRK10475
Location:31 → 75

PRK10475; 23S rRNA pseudouridine synthase F; Provisional
NM_001166539.1 → NP_001160011.1 high mobility group protein HMG-I/HMG-Y isoform b

See identical proteins and their annotated locations for NP_001160011.1

Status: REVIEWED

Description

Transcript Variant: This variant (7) differs in the 5' UTR and uses an alternate, in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 6 through 10 encode the same isoform (b), also known as isoform Y.

Source sequence(s)

AK171334, AV018894, BY270784, GH454882

Consensus CDS

CCDS50044.1

UniProtKB/TrEMBL

A0A338P6G6, Q3TVP0

Related

ENSMUSP00000156327.2, ENSMUST00000231825.2

Conserved Domains (1) summary

PRK10475
Location:31 → 75

PRK10475; 23S rRNA pseudouridine synthase F; Provisional
NM_001166540.1 → NP_001160012.1 high mobility group protein HMG-I/HMG-Y isoform b

See identical proteins and their annotated locations for NP_001160012.1

Status: REVIEWED

Description

Transcript Variant: This variant (8) differs in the 5' UTR and uses an alternate, in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 6 through 10 encode the same isoform (b), also known as isoform Y.

Source sequence(s)

AK155661, AK171334, AV018894, BY165675, BY270784

Consensus CDS

CCDS50044.1

UniProtKB/TrEMBL

A0A338P6G6, Q3TVP0

Related

ENSMUSP00000156044.2, ENSMUST00000232552.2

Conserved Domains (1) summary

PRK10475
Location:31 → 75

PRK10475; 23S rRNA pseudouridine synthase F; Provisional
NM_001166541.1 → NP_001160013.1 high mobility group protein HMG-I/HMG-Y isoform b

See identical proteins and their annotated locations for NP_001160013.1

Status: REVIEWED

Description

Transcript Variant: This variant (9) differs in the 5' UTR and uses an alternate, in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 6 through 10 encode the same isoform (b), also known as isoform Y.

Source sequence(s)

AK155661, AK171334, AV018894, BY270784

Consensus CDS

CCDS50044.1

UniProtKB/TrEMBL

A0A338P6G6, Q3TVP0

Related

ENSMUSP00000110538.4, ENSMUST00000114888.11

Conserved Domains (1) summary

PRK10475
Location:31 → 75

PRK10475; 23S rRNA pseudouridine synthase F; Provisional
NM_001166542.1 → NP_001160014.1 high mobility group protein HMG-I/HMG-Y isoform b

See identical proteins and their annotated locations for NP_001160014.1

Status: REVIEWED

Description

Transcript Variant: This variant (10) differs in the 5' UTR and uses an alternate, in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 6 through 10 encode the same isoform (b), also known as isoform Y.

Source sequence(s)

AK155661, AK171334, AV018894, BY270784

Consensus CDS

CCDS50044.1

UniProtKB/TrEMBL

A0A338P6G6, Q3TVP0

Related

ENSMUSP00000155876.2, ENSMUST00000231358.2

Conserved Domains (1) summary

PRK10475
Location:31 → 75

PRK10475; 23S rRNA pseudouridine synthase F; Provisional
NM_001166543.1 → NP_001160015.1 high mobility group protein HMG-I/HMG-Y isoform c

See identical proteins and their annotated locations for NP_001160015.1

Status: REVIEWED

Description

Transcript Variant: This variant (11) differs in the 5' UTR and uses an alternate, in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (c) is shorter than isoform a. Variants 11 and 12 encode the same isoform (c).

Source sequence(s)

AK171334, AV018894, BY165675, BY270784

Consensus CDS

CCDS89033.1

UniProtKB/TrEMBL

Q3TE85

Related

ENSMUSP00000155874.2, ENSMUST00000232253.2

Conserved Domains (1) summary

pfam06217
Location:4 → 101

GAGA_bind; GAGA binding protein-like family
NM_001166544.1 → NP_001160016.1 high mobility group protein HMG-I/HMG-Y isoform c

See identical proteins and their annotated locations for NP_001160016.1

Status: REVIEWED

Description

Transcript Variant: This variant (12) differs in the 5' UTR and uses an alternate, in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (c) is shorter than isoform a. Variants 11 and 12 encode the same isoform (c).

Source sequence(s)

AK171334, AV018894, BY270784

Consensus CDS

CCDS89033.1

UniProtKB/TrEMBL

Q3TE85

Related

ENSMUSP00000113068.3, ENSMUST00000117600.9

Conserved Domains (1) summary

pfam06217
Location:4 → 101

GAGA_bind; GAGA binding protein-like family
NM_001166545.1 → NP_001160017.1 high mobility group protein HMG-I/HMG-Y isoform d

Status: REVIEWED

Description

Transcript Variant: This variant (13) differs in the 5' UTR and uses an alternate, in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (d) is longer than isoform a.

Source sequence(s)

AK171334, AV018894, BY270784, CF951929

Consensus CDS

CCDS89032.1

UniProtKB/TrEMBL

A0A338P6E8

Related

ENSMUSP00000155922.2, ENSMUST00000231796.2
NM_001166546.1 → NP_001160018.1 high mobility group protein HMG-I/HMG-Y isoform e

Status: REVIEWED

Description

Transcript Variant: This variant (14) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform e, which has a longer and distinct C-terminus, compared to isoform a.

Source sequence(s)

AK171334, AV018894, BY270784

Consensus CDS

CCDS89034.1

UniProtKB/TrEMBL

A0A338P6F6

Related

ENSMUSP00000155966.2, ENSMUST00000231866.2
NM_001412718.1 → NP_001399647.1 high mobility group protein HMG-I/HMG-Y isoform b

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TVP0
NM_001412721.1 → NP_001399650.1 high mobility group protein HMG-I/HMG-Y isoform f

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6D0
NM_001412722.1 → NP_001399651.1 high mobility group protein HMG-I/HMG-Y isoform f

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6D0
NM_001412723.1 → NP_001399652.1 high mobility group protein HMG-I/HMG-Y isoform e

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6F6
NM_001412724.1 → NP_001399653.1 high mobility group protein HMG-I/HMG-Y isoform e

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6F6
NM_001412726.1 → NP_001399655.1 high mobility group protein HMG-I/HMG-Y isoform f

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6D0
NM_001412727.1 → NP_001399656.1 high mobility group protein HMG-I/HMG-Y isoform e

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6F6
NM_001412728.1 → NP_001399657.1 high mobility group protein HMG-I/HMG-Y isoform f

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6D0

Related

ENSMUSP00000155919.2, ENSMUST00000231243.2
NM_001412729.1 → NP_001399658.1 high mobility group protein HMG-I/HMG-Y isoform d

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6E8
NM_001412730.1 → NP_001399659.1 high mobility group protein HMG-I/HMG-Y isoform d

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A338P6E8
NM_001412731.1 → NP_001399660.1 high mobility group protein HMG-I/HMG-Y isoform a

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0
NM_001412732.1 → NP_001399661.1 high mobility group protein HMG-I/HMG-Y isoform a

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0
NM_001412733.1 → NP_001399662.1 high mobility group protein HMG-I/HMG-Y isoform a

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0
NM_001412740.1 → NP_001399669.1 high mobility group protein HMG-I/HMG-Y isoform a

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0
NM_001412748.1 → NP_001399677.1 high mobility group protein HMG-I/HMG-Y isoform g

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412749.1 → NP_001399678.1 high mobility group protein HMG-I/HMG-Y isoform g

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412750.1 → NP_001399679.1 high mobility group protein HMG-I/HMG-Y isoform h

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412751.1 → NP_001399680.1 high mobility group protein HMG-I/HMG-Y isoform g

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412752.1 → NP_001399681.1 high mobility group protein HMG-I/HMG-Y isoform g

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412754.1 → NP_001399683.1 high mobility group protein HMG-I/HMG-Y isoform h

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412755.1 → NP_001399684.1 high mobility group protein HMG-I/HMG-Y isoform h

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412764.1 → NP_001399693.1 high mobility group protein HMG-I/HMG-Y isoform h

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412765.1 → NP_001399694.1 high mobility group protein HMG-I/HMG-Y isoform g

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412766.1 → NP_001399695.1 high mobility group protein HMG-I/HMG-Y isoform c

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TE85
NM_001412767.1 → NP_001399696.1 high mobility group protein HMG-I/HMG-Y isoform c

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TE85
NM_001412768.1 → NP_001399697.1 high mobility group protein HMG-I/HMG-Y isoform c

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TE85
NM_001412769.1 → NP_001399698.1 high mobility group protein HMG-I/HMG-Y isoform c

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TE85
NM_001412770.1 → NP_001399699.1 high mobility group protein HMG-I/HMG-Y isoform i

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412771.1 → NP_001399700.1 high mobility group protein HMG-I/HMG-Y isoform i

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412772.1 → NP_001399701.1 high mobility group protein HMG-I/HMG-Y isoform i

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412773.1 → NP_001399702.1 high mobility group protein HMG-I/HMG-Y isoform i

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412783.1 → NP_001399712.1 high mobility group protein HMG-I/HMG-Y isoform b

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TVP0
NM_001412943.1 → NP_001399872.1 high mobility group protein HMG-I/HMG-Y isoform j

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412944.1 → NP_001399873.1 high mobility group protein HMG-I/HMG-Y isoform j

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412945.1 → NP_001399874.1 high mobility group protein HMG-I/HMG-Y isoform j

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412949.1 → NP_001399878.1 high mobility group protein HMG-I/HMG-Y isoform b

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TVP0
NM_001412950.1 → NP_001399879.1 high mobility group protein HMG-I/HMG-Y isoform b

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

Q3TVP0
NM_001412951.1 → NP_001399880.1 high mobility group protein HMG-I/HMG-Y isoform k

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A384DV79
NM_001412952.1 → NP_001399881.1 high mobility group protein HMG-I/HMG-Y isoform k

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A384DV79

Related

ENSMUSP00000113011.3, ENSMUST00000117254.9
NM_001412953.1 → NP_001399882.1 high mobility group protein HMG-I/HMG-Y isoform k

Status: REVIEWED

Source sequence(s)

AC127341

UniProtKB/TrEMBL

A0A384DV79
NM_001412954.1 → NP_001399883.1 high mobility group protein HMG-I/HMG-Y isoform L

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412955.1 → NP_001399884.1 high mobility group protein HMG-I/HMG-Y isoform m

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412956.1 → NP_001399885.1 high mobility group protein HMG-I/HMG-Y isoform m

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412957.1 → NP_001399886.1 high mobility group protein HMG-I/HMG-Y isoform m

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412958.1 → NP_001399887.1 high mobility group protein HMG-I/HMG-Y isoform n

Status: REVIEWED

Source sequence(s)

AC127341
NM_001412959.1 → NP_001399888.1 high mobility group protein HMG-I/HMG-Y isoform n

Status: REVIEWED

Source sequence(s)

AC127341
NM_001413142.1 → NP_001400071.1 high mobility group protein HMG-I/HMG-Y isoform r

Status: REVIEWED

Source sequence(s)

AC127341
NM_001413143.1 → NP_001400072.1 high mobility group protein HMG-I/HMG-Y isoform q

Status: REVIEWED

Source sequence(s)

AC127341
NM_001413144.1 → NP_001400073.1 high mobility group protein HMG-I/HMG-Y isoform p

Status: REVIEWED

Source sequence(s)

AC127341
NM_016660.3 → NP_057869.2 high mobility group protein HMG-I/HMG-Y isoform a

See identical proteins and their annotated locations for NP_057869.2

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes isoform a. Variants 1 through 5 encode the same isoform (a), also known as isoform I.

Source sequence(s)

AK171334, AV018894, BM937661, CF730372

Consensus CDS

CCDS28564.1

UniProtKB/Swiss-Prot

P17095, Q91WV2, Q924L7, Q924L8

UniProtKB/TrEMBL

Q566K0

Related

ENSMUSP00000156199.2, ENSMUST00000231874.2

Conserved Domains (1) summary

pfam06217
Location:4 → 87

GAGA_bind; GAGA binding protein-like family