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    Mfsd4b4 major facilitator superfamily domain containing 4B4 [ Mus musculus (house mouse) ]

    Gene ID: 213332, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Mfsd4b4provided by MGI
    Official Full Name
    major facilitator superfamily domain containing 4B4provided by MGI
    Primary source
    MGI:MGI:3035041
    See related
    Ensembl:ENSMUSG00000096687 AllianceGenome:MGI:3035041
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable glucose transmembrane transporter activity. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary adult (RPKM 4.3), limb E14.5 (RPKM 4.1) and 28 other tissues See more
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    Genomic context

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    Location:
    10 B1; 10 21.27 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (39766009..39775202, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (39890013..39899206, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene REV3 like, DNA directed polymerase zeta catalytic subunit Neighboring gene STARR-seq mESC enhancer starr_26404 Neighboring gene STARR-seq mESC enhancer starr_26405 Neighboring gene predicted gene, 22105 Neighboring gene STARR-seq mESC enhancer starr_26406 Neighboring gene 60S ribosomal protein L15 pseudogene Neighboring gene isopentenyl-diphosphate delta isomerase, pseudogene 3 Neighboring gene major facilitator superfamily domain containing 4B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    2. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    major facilitator superfamily domain containing 4B4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001384225.1 → NP_001371154.1  major facilitator superfamily domain containing 4B4 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: Variants 1and 3 encode the longer isoform (1).
      Source sequence(s)
      AC118733
      UniProtKB/TrEMBL
      J3QNS5
      Related
      ENSMUSP00000136934.2, ENSMUST00000178045.9
      Conserved Domains (1) summary
      cl28910
      Location:7 → 405
      MFS; Major Facilitator Superfamily

    2. NM_001384226.1 → NP_001371155.1  major facilitator superfamily domain containing 4B4 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: Variants 2, 4, and 5 encode the shorter isoform (2).
      Source sequence(s)
      AC118733
      UniProtKB/TrEMBL
      J3QPW5
      Related
      ENSMUSP00000137516.2, ENSMUST00000178563.3
      Conserved Domains (1) summary
      cl28910
      Location:1 → 359
      MFS; Major Facilitator Superfamily

    3. NM_001416571.1 → NP_001403500.1  major facilitator superfamily domain containing 4B4 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: Variants 1and 3 encode the longer isoform (1).
      Source sequence(s)
      AC118733
      UniProtKB/TrEMBL
      J3QNS5

    4. NM_001416572.1 → NP_001403501.1  major facilitator superfamily domain containing 4B4 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: Variants 2, 4, and 5 encode the shorter isoform (2).
      Source sequence(s)
      AC118733
      UniProtKB/TrEMBL
      J3QPW5

    5. NM_001416573.1 → NP_001403502.1  major facilitator superfamily domain containing 4B4 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: Variants 2, 4, and 5 encode the shorter isoform (2).
      Source sequence(s)
      AC118733
      UniProtKB/TrEMBL
      J3QPW5

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      39766009..39775202 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155725.1 → XP_036011618.1  major facilitator superfamily domain containing 4B4 isoform X1

      UniProtKB/TrEMBL
      J3QNS5
      Conserved Domains (1) summary
      cl28910
      Location:7 → 405
      MFS; Major Facilitator Superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_008345.1: Suppressed sequence

      Description
      NG_008345.1: This RefSeq was permanently suppressed because there is sufficient evidence that this locus is transcribed.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials