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    H4c11 H4 clustered histone 11 [ Mus musculus (house mouse) ]

    Gene ID: 319159, updated on 8-Feb-2024

    Summary

    Official Symbol
    H4c11provided by MGI
    Official Full Name
    H4 clustered histone 11provided by MGI
    Primary source
    MGI:MGI:2448436
    See related
    Ensembl:ENSMUSG00000067455 AllianceGenome:MGI:2448436
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H4c1; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4c12; H4c14; H4c16; H4f16; Hist1h4j
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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    Genomic context

    Location:
    13 A3.1; 13 7.94 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (21919204..21919626)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21735034..21735456)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E261 Neighboring gene H2A clustered histone 14, pseudogene Neighboring gene H2B clustered histone 14 Neighboring gene STARR-seq mESC enhancer starr_33860 Neighboring gene STARR-seq mESC enhancer starr_33862 Neighboring gene H4 clustered histone 12 Neighboring gene H2A clustered histone 15

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of CENP-A containing nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H4
    Names
    histone 1, H4j
    histone cluster 1, H4j

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178210.2NP_835582.1  histone H4

      See identical proteins and their annotated locations for NP_835582.1

      Status: REVIEWED

      Source sequence(s)
      AL589651
      Consensus CDS
      CCDS26291.1
      UniProtKB/Swiss-Prot
      A0AUM5, A4FUP8, A4QMY0, P62806, Q0VDL9, Q2M2Q5, Q5T006, Q6PDS7, Q811M0, Q9D0C9, Q9D6Q8
      UniProtKB/TrEMBL
      B2RTM0
      Related
      ENSMUSP00000085006.5, ENSMUST00000087714.6
      Conserved Domains (1) summary
      PLN00035
      Location:1103
      PLN00035; histone H4; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      21919204..21919626
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)