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    Ugt3a1 UDP glycosyltransferases 3 family, polypeptide A1 [ Mus musculus (house mouse) ]

    Gene ID: 105887, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ugt3a1provided by MGI
    Official Full Name
    UDP glycosyltransferases 3 family, polypeptide A1provided by MGI
    Primary source
    MGI:MGI:2146055
    See related
    Ensembl:ENSMUSG00000072664 AllianceGenome:MGI:2146055
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Enables UDP-glycosyltransferase activity. Predicted to act upstream of or within cellular response to genistein. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in trigeminal ganglion. Orthologous to several human genes including UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in kidney adult (RPKM 77.1) and liver adult (RPKM 30.5) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    15; 15 A1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (9279908..9315124)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (9279822..9315038)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3131 Neighboring gene S-phase kinase-associated protein 2 Neighboring gene LMBR1 domain containing 2 Neighboring gene STARR-seq mESC enhancer starr_37931 Neighboring gene STARR-seq mESC enhancer starr_37932 Neighboring gene UDP glycosyltransferases 3 family pseudogene Neighboring gene UDP glycosyltransferases 3 family, polypeptide A1 pseudogene Neighboring gene UDP glycosyltransferases 3 family, polypeptide A2 Neighboring gene STARR-seq mESC enhancer starr_37936

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes. Meech R, et al. J Biol Chem, 2012 Jul 13. PMID 22621930, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP-glycosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables glucuronosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucuronosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to genistein ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of UDP-N-acetylglucosamine transferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of UDP-N-acetylglucosamine transferase complex ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucuronosyltransferase 3A1
    Names
    UDP glucuronosyltransferase 3 family, polypeptide A1
    UDPGT 3A1
    NP_997099.2
    XP_006520074.1
    XP_006520075.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207216.2 → NP_997099.2  UDP-glucuronosyltransferase 3A1 precursor

      See identical proteins and their annotated locations for NP_997099.2

      Status: VALIDATED

      Source sequence(s)
      AC132893, AI746748, AK143745, BY006031
      Consensus CDS
      CCDS27374.1
      UniProtKB/Swiss-Prot
      Q3UP75, Q8R0Y5
      Related
      ENSMUSP00000022861.9, ENSMUST00000022861.9
      Conserved Domains (2) summary
      PHA03392
      Location:235 → 488
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:24 → 488
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      9279908..9315124
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520012.4 → XP_006520075.1  UDP-glucuronosyltransferase 3A1 isoform X2

      Conserved Domains (1) summary
      pfam00201
      Location:24 → 281
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    2. XM_006520011.3 → XP_006520074.1  UDP-glucuronosyltransferase 3A1 isoform X1

      Conserved Domains (1) summary
      pfam00201
      Location:1 → 359
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UP75.1 GenPept UniProtKB/Swiss-Prot:Q3UP75

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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