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    1600012H06Rik RIKEN cDNA 1600012H06 gene [ Mus musculus (house mouse) ]

    Gene ID: 67912, updated on 5-Mar-2024

    Summary

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    Official Symbol
    1600012H06Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 1600012H06 geneprovided by MGI
    Primary source
    MGI:MGI:1915162
    See related
    Ensembl:ENSMUSG00000050088 AllianceGenome:MGI:1915162
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to act upstream of or within apoptotic process. Predicted to be located in extracellular region. Is expressed in several structures, including head mesenchyme; heart ventricle; lung; pituitary gland; and tongue. Orthologous to human C6orf120 (chromosome 6 open reading frame 120). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 18.4), colon adult (RPKM 16.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See 1600012H06Rik in Genome Data Viewer
    Location:
    17 A2; 17 8.95 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (15163446..15166201)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (14943184..14945939)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_41895 Neighboring gene predicted gene, 23352 Neighboring gene WD repeat domain 27 Neighboring gene STARR-seq mESC enhancer starr_41897 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:15046536-15046719 Neighboring gene STARR-positive B cell enhancer ABC_E9166 Neighboring gene PHD finger protein 10 Neighboring gene dynein light chain Tctex-type 2A3 Neighboring gene STARR-seq mESC enhancer starr_41898 Neighboring gene ER membrane associated RNA degradation like 2 Neighboring gene predicted gene 3255

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UPF0669 protein C6orf120 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083880.1 → NP_001077349.1  UPF0669 protein C6orf120 homolog precursor

      See identical proteins and their annotated locations for NP_001077349.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has an alternate splice site in the 5' UTR, compared to variant 1. All variants encode the same protein.
      Source sequence(s)
      AC154411
      Consensus CDS
      CCDS37444.1
      UniProtKB/Swiss-Prot
      Q80ST2, Q8CEI9, Q9CU86, Q9DAY5
      UniProtKB/TrEMBL
      Q05CC8
      Related
      ENSMUSP00000133628.2, ENSMUST00000174004.2
      Conserved Domains (1) summary
      pfam17065
      Location:1 → 185
      UPF0669; Putative cytokine, C6ORF120

    2. NM_001083881.1 → NP_001077350.1  UPF0669 protein C6orf120 homolog precursor

      See identical proteins and their annotated locations for NP_001077350.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) and variants 2, 3 and 4 encode the same protein.
      Source sequence(s)
      AC154411, AK150772, AU254107, BB610149
      Consensus CDS
      CCDS37444.1
      UniProtKB/Swiss-Prot
      Q80ST2, Q8CEI9, Q9CU86, Q9DAY5
      UniProtKB/TrEMBL
      Q05CC8
      Related
      ENSMUSP00000125970.3, ENSMUST00000164837.3
      Conserved Domains (1) summary
      pfam17065
      Location:1 → 185
      UPF0669; Putative cytokine, C6ORF120

    3. NM_001083882.1 → NP_001077351.1  UPF0669 protein C6orf120 homolog precursor

      See identical proteins and their annotated locations for NP_001077351.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks a splice junction in the 5' UTR, compared to variant 1. All variants encode the same protein.
      Source sequence(s)
      AK076441, AK083064, AU254107, BB610149
      Consensus CDS
      CCDS37444.1
      UniProtKB/Swiss-Prot
      Q80ST2, Q8CEI9, Q9CU86, Q9DAY5
      UniProtKB/TrEMBL
      Q05CC8
      Conserved Domains (1) summary
      pfam17065
      Location:1 → 185
      UPF0669; Putative cytokine, C6ORF120

    4. NM_026451.2 → NP_080727.2  UPF0669 protein C6orf120 homolog precursor

      See identical proteins and their annotated locations for NP_080727.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate splice site in the 5' UTR, compared to variant 1. All variants encode the same protein.
      Source sequence(s)
      AK005427, AK083064, AU254107, BB610149
      Consensus CDS
      CCDS37444.1
      UniProtKB/Swiss-Prot
      Q80ST2, Q8CEI9, Q9CU86, Q9DAY5
      UniProtKB/TrEMBL
      Q05CC8
      Related
      ENSMUSP00000093344.5, ENSMUST00000052691.9
      Conserved Domains (1) summary
      pfam17065
      Location:1 → 185
      UPF0669; Putative cytokine, C6ORF120

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      15163446..15166201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9DAY5.1 GenPept UniProtKB/Swiss-Prot:Q9DAY5

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    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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