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    Poldip3 polymerase (DNA-directed), delta interacting protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 73826, updated on 11-Apr-2024

    Summary

    Official Symbol
    Poldip3provided by MGI
    Official Full Name
    polymerase (DNA-directed), delta interacting protein 3provided by MGI
    Primary source
    MGI:MGI:1921076
    See related
    Ensembl:ENSMUSG00000041815 AllianceGenome:MGI:1921076
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SKAR; PDIP46; mKIAA1649; 1110008P04Rik
    Summary
    Predicted to enable mRNA binding activity. Involved in poly(A)+ mRNA export from nucleus. Predicted to be located in cytoplasmic ribonucleoprotein granule. Predicted to be active in nuclear speck. Is expressed in several structures, including brain and retina layer. Orthologous to human POLDIP3 (DNA polymerase delta interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary adult (RPKM 39.9), thymus adult (RPKM 34.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    15 E1; 15 39.4 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (83010169..83033579, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (83125968..83149378, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3150 Neighboring gene predicted gene, 41366 Neighboring gene STARR-positive B cell enhancer ABC_E7402 Neighboring gene serine hydrolase-like Neighboring gene ribosomal RNA processing 7 homolog A Neighboring gene RNA U12, small nuclear Neighboring gene cytochrome b5 reductase 3 Neighboring gene STARR-positive B cell enhancer ABC_E4142

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1649

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in poly(A)+ mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in poly(A)+ mRNA export from nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in poly(A)+ mRNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of translation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    polymerase delta-interacting protein 3
    Names
    S6K1 Aly/REF-like target
    polymerase delta interacting protein 46

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347082.1NP_001334011.1  polymerase delta-interacting protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK083924, AK150130, BB711286, BC058225, BY298213
      Consensus CDS
      CCDS84183.1
      UniProtKB/TrEMBL
      Q3U8V1, Q3UDD3
      Related
      ENSMUSP00000097944.5, ENSMUST00000100375.11
    2. NM_178627.4NP_848742.1  polymerase delta-interacting protein 3 isoform 1

      See identical proteins and their annotated locations for NP_848742.1

      Status: VALIDATED

      Source sequence(s)
      AL591952
      Consensus CDS
      CCDS27697.1
      UniProtKB/Swiss-Prot
      B2FDB4, Q6PE83, Q80X99, Q8BG81, Q8CI28
      UniProtKB/TrEMBL
      Q3U8V1
      Related
      ENSMUSP00000054548.7, ENSMUST00000058793.14

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      83010169..83033579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)