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    Vma21 vacuolar ATPase assembly factor VMA21 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501658, updated on 13-Apr-2024

    Summary

    Symbol
    Vma21provided by RGD
    Full Name
    vacuolar ATPase assembly factor VMA21provided by RGD
    Primary source
    RGD:1566155
    See related
    Ensembl:ENSRNOG00000048606 AllianceGenome:RGD:1566155
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566155
    Summary
    Predicted to be involved in vacuolar proton-transporting V-type ATPase complex assembly. Predicted to be located in lysosome. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in X-linked myopathy with excessive autophagy. Orthologous to human VMA21 (vacuolar ATPase assembly factor VMA21). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 90.2), Kidney (RPKM 74.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    Location:
    Xq37
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (154536493..154545794)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (149491709..149501010)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (70142561..70151833, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 50 Neighboring gene low molecular weight phosphotyrosine protein phosphatase-like Neighboring gene ubiquitin specific peptidase 12 like 1 Neighboring gene pumilio RNA-binding family member 3 like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    vacuolar ATPase assembly integral membrane protein VMA21
    Names
    VMA21 vacuolar H+-ATPase homolog
    VMA21, vacuolar ATPase assembly factor
    vacuolar ATPase assembly integral membrane protein VMA21-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402260.1NP_001389189.1  vacuolar ATPase assembly integral membrane protein VMA21 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A8I6A8R1
      Related
      ENSRNOP00000088143.1, ENSRNOT00000120047.1
    2. NM_001402261.1NP_001389190.1  vacuolar ATPase assembly integral membrane protein VMA21 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6KUL7, D3ZM03
      Related
      ENSRNOP00000064271.1, ENSRNOT00000071269.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      154536493..154545794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)