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    Katnip katanin interacting protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361646, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Katnipprovided by RGD
    Official Full Name
    katanin interacting proteinprovided by RGD
    Primary source
    RGD:1595846
    See related
    Ensembl:ENSRNOG00000016635 AllianceGenome:RGD:1595846
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307324
    Summary
    Predicted to act upstream of or within cerebrospinal fluid circulation. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in Joubert syndrome 26. Orthologous to human KATNIP (katanin interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 44.1), Lung (RPKM 43.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    1q36
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (189700838..189867402)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (180270194..180436766)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (197098621..197265840)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097359 Neighboring gene interleukin 21 receptor Neighboring gene general transcription factor IIIC subunit 1 Neighboring gene GSG1-like Neighboring gene uncharacterized LOC134483828 Neighboring gene exportin 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome. Sanders AA, et al. Genome Biol, 2015 Dec 29. PMID 26714646, Free PMC Article
    2. Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. Böhm D, et al. Oncol Rep, 2012 Aug. PMID 22664934, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within cerebrospinal fluid circulation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    katanin-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395755.1 → NP_001382684.1  katanin-interacting protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      D3ZX12, F1LX85
      Related
      ENSRNOP00000022365.6, ENSRNOT00000022365.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      189700838..189867402
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082889.2 → XP_038938817.1  katanin-interacting protein isoform X4

      UniProtKB/TrEMBL
      A0A8I6AUE5
      Related
      ENSRNOP00000095945.1
      Conserved Domains (1) summary
      pfam14652
      Location:1130 → 1449
      DUF4457; Domain of unknown function (DUF4457)

    2. XM_039082891.2 → XP_038938819.1  katanin-interacting protein isoform X6

      UniProtKB/TrEMBL
      A0A8I6AUE5
      Conserved Domains (1) summary
      pfam14652
      Location:1017 → 1336
      DUF4457; Domain of unknown function (DUF4457)

    3. XM_017589397.3 → XP_017444886.1  katanin-interacting protein isoform X3

      UniProtKB/TrEMBL
      D3ZX12, F1LX85

    4. XM_006230296.5 → XP_006230358.1  katanin-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006230358.1

      UniProtKB/TrEMBL
      A6I926, D3ZX12, F1LX85
      Conserved Domains (1) summary
      pfam14652
      Location:1179 → 1498
      DUF4457; Domain of unknown function (DUF4457)

    5. XM_008759893.4 → XP_008758115.1  katanin-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_008758115.1

      UniProtKB/TrEMBL
      A6I926, D3ZX12, F1LX85
      Conserved Domains (1) summary
      pfam14652
      Location:1179 → 1498
      DUF4457; Domain of unknown function (DUF4457)

    6. XM_063267675.1 → XP_063123745.1  katanin-interacting protein isoform X7

      UniProtKB/TrEMBL
      A6I927

    7. XM_039082892.1 → XP_038938820.1  katanin-interacting protein isoform X7

      UniProtKB/TrEMBL
      A6I927, D3ZX12, F1LX85
      Conserved Domains (1) summary
      pfam14652
      Location:945 → 1264
      DUF4457; Domain of unknown function (DUF4457)

    8. XM_006230297.4 → XP_006230359.1  katanin-interacting protein isoform X2

      UniProtKB/TrEMBL
      A0A0G2JYJ4, D3ZX12, F1LX85
      Related
      ENSRNOP00000070677.2, ENSRNOT00000083248.2
      Conserved Domains (1) summary
      pfam14652
      Location:1172 → 1491
      DUF4457; Domain of unknown function (DUF4457)

    9. XM_008759894.4 → XP_008758116.1  katanin-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_008758116.1

      UniProtKB/TrEMBL
      A6I926, D3ZX12, F1LX85
      Conserved Domains (1) summary
      pfam14652
      Location:1179 → 1498
      DUF4457; Domain of unknown function (DUF4457)

    10. XM_063267670.1 → XP_063123740.1  katanin-interacting protein isoform X5

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001134574.1: Suppressed sequence

      Description
      NM_001134574.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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