Medag mesenteric estrogen-dependent adipogenesis [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Medagprovided by RGD
Official Full Name: mesenteric estrogen-dependent adipogenesisprovided by RGD
Primary source: RGD:1307396
See related: Ensembl:ENSRNOG00000000906 AllianceGenome:RGD:1307396
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1307396
Summary: Predicted to be involved in positive regulation of fat cell differentiation. Predicted to be active in cytoplasm. Orthologous to human MEDAG (mesenteric estrogen dependent adipogenesis). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 94.9), Adrenal (RPKM 94.3) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12p11

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (10649526..10670913, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (5613191..5634583, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (6711745..6730959, complement)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in positive regulation of fat cell differentiation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: mesenteric estrogen-dependent adipogenesis protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398808.1 → NP_001385737.1 mesenteric estrogen-dependent adipogenesis protein isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000012

UniProtKB/TrEMBL

D3ZTT1

Related

ENSRNOP00000001205.5, ENSRNOT00000001205.8
NM_001398809.1 → NP_001385738.1 mesenteric estrogen-dependent adipogenesis protein isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000012

UniProtKB/TrEMBL

A6K165