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    H2ac24 H2A clustered histone 24 [ Mus musculus (house mouse) ]

    Gene ID: 319171, updated on 11-Apr-2024

    Summary

    Official Symbol
    H2ac24provided by MGI
    Official Full Name
    H2A clustered histone 24provided by MGI
    Primary source
    MGI:MGI:3710573
    See related
    Ensembl:ENSMUSG00000094777 AllianceGenome:MGI:3710573
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm11276; Hist1h2ap
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Sep 2015]
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    Genomic context

    See H2ac24 in Genome Data Viewer
    Location:
    13 A3.1; 13 8.0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (22017194..22017645, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21833024..21833475, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53778 Neighboring gene STARR-seq mESC enhancer starr_33867 Neighboring gene H4 clustered histone 18 Neighboring gene H2B clustered histone 24 Neighboring gene STARR-positive B cell enhancer mm9_chr13:21932431-21932732 Neighboring gene nuclear encoded tRNA leucine 2 (anticodon TAA)

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nucleosomal DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of CENP-A containing nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H2A type 1-P
    Names
    Histone H2A type 1-O
    Histone H2A type 1-P
    histone H2A type 1
    histone cluster 1, H2ap

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178185.2NP_835492.1  histone H2A type 1-P

      See identical proteins and their annotated locations for NP_835492.1

      Status: REVIEWED

      Source sequence(s)
      AL589879
      Consensus CDS
      CCDS26301.1
      UniProtKB/Swiss-Prot
      C0HKE1, C0HKE2, C0HKE3, C0HKE4, C0HKE5, C0HKE6, C0HKE7, C0HKE8, C0HKE9, P10812, P22752, Q149U0, Q5SZZ2
      UniProtKB/TrEMBL
      A0AUV1, B2RVF0
      Related
      ENSMUSP00000080088.6, ENSMUST00000081342.7
      Conserved Domains (1) summary
      PTZ00017
      Location:1130
      PTZ00017; histone H2A; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      22017194..22017645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)