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    atg6 beclin family protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361548, updated on 11-Apr-2024

    Summary

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    Gene symbol
    atg6
    Gene description
    beclin family protein
    Primary source
    PomBase:SPAC20G8.10c
    Locus tag
    SPAC20G8.10c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC3A12.01c
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1418900..1420497, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative protein Fft1 Neighboring gene putative ribosome biogenesis ATPase Neighboring gene tRNA-Cys Neighboring gene putative inorganic diphosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic regulation of mitotic competence in G(0) quiescent cells. Sajiki K, et al. Sci Adv, 2018 Aug. PMID 30116786, Free PMC Article
    2. Visual detection of binary, ternary and quaternary protein interactions in fission yeast using a Pil1 co-tethering assay. Yu ZQ, et al. J Cell Sci, 2021 Oct 1. PMID 34499173
    3. Atg38-Atg8 interaction in fission yeast establishes a positive feedback loop to promote autophagy. Yu ZQ, et al. Autophagy, 2020 Nov. PMID 31941401, Free PMC Article
    4. Global analysis of fission yeast mating genes reveals new autophagy factors. Sun LL, et al. PLoS Genet, 2013. PMID 23950735, Free PMC Article
    5. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables phosphatidylinositol 3-kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to nitrogen starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in late endosome to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylinositol biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in fungal-type vacuole membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in phagophore assembly site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in phagophore assembly site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in phagophore assembly site membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of phosphatidylinositol 3-kinase complex, class III, type I EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of phosphatidylinositol 3-kinase complex, class III, type I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class III, type II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of phosphatidylinositol 3-kinase complex, class III, type II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beclin family protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1418900..1420497 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356013.1 → NP_001342824.1  beclin family protein [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P87116, P87117
      Conserved Domains (1) summary
      pfam04111
      Location:141 → 457
      APG6; Autophagy protein Apg6
    Nucleotide Protein
    Heading Accession and Version

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