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    pdb1 pyruvate dehydrogenase e1 component beta subunit Pdb1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540273, updated on 11-Apr-2024

    Summary

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    Gene symbol
    pdb1
    Gene description
    pyruvate dehydrogenase e1 component beta subunit Pdb1
    Locus tag
    SPBC30D10.13c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3070316..3072018)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene putative snoRNP assembly factor Naf1 Neighboring gene putative dienelactone hydrolase family protein Neighboring gene putative mitochondrial ribosomal protein subunit S27 Neighboring gene pig-Q Neighboring gene phosphatidylinositol kinase Tor1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations which reduce levels of pyruvate dehydrogenase in Schizosaccharomyces pombe cause a requirement for arginine or glutamine. Cavan G, et al. FEMS Microbiol Lett, 1994 Dec 15. PMID 7851743
    2. Cloning and sequence of a gene encoding the pyruvate dehydrogenase E1 beta subunit of Schizosaccharomyces pombe. Cavan G, et al. Gene, 1995 Jan 11. PMID 7828917
    3. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article
    4. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
    5. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables pyruvate dehydrogenase (acetyl-transferring) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pyruvate dehydrogenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetyl-CoA biosynthetic process from pyruvate IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in acetyl-CoA biosynthetic process from pyruvate IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in aerobic respiration IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion HDA PubMed 
    part_of pyruvate dehydrogenase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    pyruvate dehydrogenase e1 component beta subunit Pdb1
    NP_596272.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3070316..3072018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022193.2 → NP_596272.1  pyruvate dehydrogenase e1 component beta subunit Pdb1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596272.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09171
      Conserved Domains (3) summary
      cd07036
      Location:42 → 208
      TPP_PYR_E1-PDHc-beta_like; Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins
      PLN02683
      Location:25 → 364
      PLN02683; pyruvate dehydrogenase E1 component subunit beta
      pfam02780
      Location:231 → 355
      Transketolase_C; Transketolase, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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