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    Cmc2 C-X9-C motif containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 66531, updated on 16-Apr-2024

    Summary

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    Official Symbol
    Cmc2provided by MGI
    Official Full Name
    C-X9-C motif containing 2provided by MGI
    Primary source
    MGI:MGI:1913781
    See related
    Ensembl:ENSMUSG00000014633 AllianceGenome:MGI:1913781
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DC13; 1110046L09Rik; 2310061C15Rik
    Summary
    Predicted to be active in mitochondrion. Orthologous to human CMC2 (C-X9-C motif containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver E14 (RPKM 8.3), heart adult (RPKM 7.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    8 E1; 8 63.28 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (117615424..117671061, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (116888685..116944322, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene translation machinery-associated protein 7 pseudogene Neighboring gene predicted gene, 42045 Neighboring gene STARR-seq mESC enhancer starr_22803 Neighboring gene STARR-positive B cell enhancer ABC_E6690 Neighboring gene centromere protein N Neighboring gene ATM interactor Neighboring gene RIKEN cDNA 1700030J22 gene Neighboring gene STARR-positive B cell enhancer ABC_E2878 Neighboring gene STARR-positive B cell enhancer ABC_E6691 Neighboring gene STARR-positive B cell enhancer ABC_E3808 Neighboring gene glycine cleavage system protein H (aminomethyl carrier)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    COX assembly mitochondrial protein 2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026844.3 → NP_081120.2  COX assembly mitochondrial protein 2 homolog

      See identical proteins and their annotated locations for NP_081120.2

      Status: VALIDATED

      Source sequence(s)
      AC121101, AK002429
      Consensus CDS
      CCDS40489.1
      UniProtKB/Swiss-Prot
      Q8CEV6, Q8K199
      Related
      ENSMUSP00000120966.2, ENSMUST00000148235.8
      Conserved Domains (1) summary
      pfam08583
      Location:1 → 70
      Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      117615424..117671061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531282.3 → XP_006531345.1  COX assembly mitochondrial protein 2 homolog isoform X1

      See identical proteins and their annotated locations for XP_006531345.1

      UniProtKB/Swiss-Prot
      Q8CEV6, Q8K199
      Conserved Domains (1) summary
      pfam08583
      Location:1 → 70
      Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like

    2. XM_011248485.3 → XP_011246787.1  COX assembly mitochondrial protein 2 homolog isoform X1

      See identical proteins and their annotated locations for XP_011246787.1

      UniProtKB/Swiss-Prot
      Q8CEV6, Q8K199
      Conserved Domains (1) summary
      pfam08583
      Location:1 → 70
      Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8K199.1 GenPept UniProtKB/Swiss-Prot:Q8K199

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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