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    Pigm phosphatidylinositol glycan anchor biosynthesis, class M [ Mus musculus (house mouse) ]

    Gene ID: 67556, updated on 30-Apr-2024

    Summary

    Official Symbol
    Pigmprovided by MGI
    Official Full Name
    phosphatidylinositol glycan anchor biosynthesis, class Mprovided by MGI
    Primary source
    MGI:MGI:1914806
    See related
    Ensembl:ENSMUSG00000050229 AllianceGenome:MGI:1914806
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933437L05Rik; C920011G20Rik
    Summary
    Predicted to enable mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be part of glycosylphosphatidylinositol-mannosyltransferase I complex. Is expressed in several structures, including alimentary system; aorta; genitourinary system; nervous system; and thymus. Orthologous to human PIGM (phosphatidylinositol glycan anchor biosynthesis class M). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See Pigm in Genome Data Viewer
    Location:
    1 H3; 1 79.73 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (172204098..172211666)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (172376531..172384099)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 9 Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 10 Neighboring gene STARR-positive B cell enhancer ABC_E3331 Neighboring gene STARR-positive B cell enhancer ABC_E4390 Neighboring gene STARR-positive B cell enhancer mm9_chr1:174340789-174341090 Neighboring gene STARR-seq mESC enhancer starr_03060 Neighboring gene STARR-positive B cell enhancer ABC_E5854 Neighboring gene STARR-positive B cell enhancer ABC_E5855 Neighboring gene STARR-positive B cell enhancer ABC_E2020 Neighboring gene ribosomal protein SA pseudogene Neighboring gene SLAM family member 9

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables alpha-1,4-mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycolipid mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mannosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in GPI anchor biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    part_of glycosylphosphatidylinositol-mannosyltransferase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GPI mannosyltransferase 1
    Names
    GPI mannosyltransferase I
    GPI-MT-I
    PIG-M
    phosphatidylinositol glycan, class M
    phosphatidylinositol-glycan biosynthesis class M protein
    NP_080510.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026234.4NP_080510.1  GPI mannosyltransferase 1

      See identical proteins and their annotated locations for NP_080510.1

      Status: VALIDATED

      Source sequence(s)
      AC074311
      Consensus CDS
      CCDS15513.1
      UniProtKB/Swiss-Prot
      Q8C2R7, Q8C917, Q99J22, Q9D315
      Related
      ENSMUSP00000052838.3, ENSMUST00000052455.4
      Conserved Domains (1) summary
      pfam05007
      Location:140408
      Mannosyl_trans; Mannosyltransferase (PIG-M)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      172204098..172211666
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)