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    Vat1l vesicle amine transport protein 1 like [ Mus musculus (house mouse) ]

    Gene ID: 270097, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Vat1lprovided by MGI
    Official Full Name
    vesicle amine transport protein 1 likeprovided by MGI
    Primary source
    MGI:MGI:2142534
    See related
    Ensembl:ENSMUSG00000046844 AllianceGenome:MGI:2142534
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1576; 9430073I07
    Summary
    Predicted to enable oxidoreductase activity and zinc ion binding activity. Is expressed in several structures, including body wall mesenchyme; central nervous system; limb mesenchyme; peripheral nervous system ganglion; and trigeminal nerve. Orthologous to human VAT1L (vesicle amine transport 1 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E18 (RPKM 30.3), cerebellum adult (RPKM 24.6) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    8 E1; 8 60.62 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (114932307..115100814)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (114205281..114374074)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30107 Neighboring gene STARR-seq mESC enhancer starr_22765 Neighboring gene STARR-positive B cell enhancer ABC_E9028 Neighboring gene STARR-seq mESC enhancer starr_22767 Neighboring gene nudix hydrolase 7 Neighboring gene RIKEN cDNA 4933408N05 gene Neighboring gene STARR-positive B cell enhancer ABC_E3807 Neighboring gene STARR-seq mESC enhancer starr_22773 Neighboring gene predicted gene, 30330 Neighboring gene C-type lectin domain family 3, member a Neighboring gene WW domain-containing oxidoreductase Neighboring gene predicted gene 16116

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of Arx transcriptional targets in the developing basal forebrain. Fulp CT, et al. Hum Mol Genet, 2008 Dec 1. PMID 18799476, Free PMC Article
    2. PRC1 sustains the integrity of neural fate in the absence of PRC2 function. Sawai A, et al. Elife, 2022 Jan 7. PMID 34994686, Free PMC Article
    3. Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Osipovich AB, et al. Development, 2014 Aug. PMID 25053427, Free PMC Article
    4. 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. Berggård T, et al. J Proteome Res, 2006 Mar. PMID 16512683
    5. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    synaptic vesicle membrane protein VAT-1 homolog-like
    Names
    vesicle amine transport protein 1 homolog-like (T. californica)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173016.4 → NP_766604.2  synaptic vesicle membrane protein VAT-1 homolog-like

      See identical proteins and their annotated locations for NP_766604.2

      Status: VALIDATED

      Source sequence(s)
      AC151980, AC151998
      Consensus CDS
      CCDS22689.1
      UniProtKB/Swiss-Prot
      Q6PGM9, Q80TB8
      Related
      ENSMUSP00000053431.7, ENSMUST00000049509.7
      Conserved Domains (1) summary
      cd08275
      Location:41 → 378
      MDR3; Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      114932307..115100814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248394.3 → XP_011246696.1  synaptic vesicle membrane protein VAT-1 homolog-like isoform X1

      Conserved Domains (1) summary
      cd08275
      Location:41 → 358
      MDR3; Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80TB8.2 GenPept UniProtKB/Swiss-Prot:Q80TB8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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