U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pdca phosducin a [ Danio rerio (zebrafish) ]

    Gene ID: 386613, updated on 27-Mar-2024

    Summary

    Official Symbol
    pdcaprovided by ZNC
    Official Full Name
    phosducin aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031023-1
    See related
    Ensembl:ENSDARG00000011886 AllianceGenome:ZFIN:ZDB-GENE-031023-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    PDC; pdc1; pdcr
    Summary
    Predicted to act upstream of or within regulation of G protein-coupled receptor signaling pathway and visual perception. Is expressed in eye and retina. Orthologous to human PDC (phosducin). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (20882954..20890429, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (21224892..21232367, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene proteoglycan 4a Neighboring gene translocated promoter region a, nuclear basket protein Neighboring gene odr-4 GPCR localization factor homolog Neighboring gene prostaglandin-endoperoxide synthase 2a Neighboring gene phospholipase A2, group IVAa (cytosolic, calcium-dependent)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within response to stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within visual perception IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in photoreceptor inner segment IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in photoreceptor outer segment IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    phosducin a
    Names
    PDCb1
    phosducin 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291500.1NP_001278429.1  phosducin a

      See identical proteins and their annotated locations for NP_001278429.1

      Status: VALIDATED

      Source sequence(s)
      CU570979
      UniProtKB/TrEMBL
      A0A8M1P6P2, F8W512
      Related
      ENSDARP00000123816.1, ENSDART00000149989.2
      Conserved Domains (1) summary
      cd02987
      Location:9216
      Phd_like_Phd; Phosducin (Phd)-like family, Phd subfamily; Phd is a cytosolic regulator of G protein functions. It specifically binds G protein betagamma (Gbg)-subunits with high affinity, resulting in the solubilization of Gbg from the plasma membrane. This impedes ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      20882954..20890429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)