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    Stk32b serine/threonine kinase 32B [ Mus musculus (house mouse) ]

    Gene ID: 64293, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Stk32bprovided by MGI
    Official Full Name
    serine/threonine kinase 32Bprovided by MGI
    Primary source
    MGI:MGI:1927552
    See related
    Ensembl:ENSMUSG00000029123 AllianceGenome:MGI:1927552
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    STKG6; Stk32; YANK2; 2510009F08Rik
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within phosphorylation. Is expressed in several structures, including cranium; hindlimb; respiratory system; sensory organ; and telencephalon. Orthologous to human STK32B (serine/threonine kinase 32B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E18 (RPKM 17.1), whole brain E14.5 (RPKM 15.3) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    5 B3; 5 20.18 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (37604169..37874503, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (37446825..37717153, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene 42935 Neighboring gene EvC ciliary complex subunit 1 Neighboring gene STARR-seq mESC enhancer starr_12901 Neighboring gene EvC ciliary complex subunit 2 Neighboring gene predicted gene 15732 Neighboring gene STARR-seq mESC enhancer starr_12902 Neighboring gene STARR-seq mESC enhancer starr_12903 Neighboring gene STARR-seq mESC enhancer starr_12904 Neighboring gene cytokine-like 1 Neighboring gene predicted gene, 40286

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis. Ruiz-Perez VL, et al. Nat Genet, 2000 Mar. PMID 10700184
    2. Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. Rattner A, et al. Elife, 2020 Oct 21. PMID 33084572, Free PMC Article
    3. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein kinase 32B
    Names
    serine threonine kinase 32
    NP_071861.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022416.3 → NP_071861.1  serine/threonine-protein kinase 32B

      See identical proteins and their annotated locations for NP_071861.1

      Status: VALIDATED

      Source sequence(s)
      AC110244, AC110565, AC158588
      Consensus CDS
      CCDS39076.1
      UniProtKB/Swiss-Prot
      Q7TMD3, Q8C4E0, Q9JJX8
      Related
      ENSMUSP00000092432.5, ENSMUST00000094836.6
      Conserved Domains (2) summary
      smart00220
      Location:23 → 272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05578
      Location:22 → 283
      STKc_Yank1; Catalytic domain of the Serine/Threonine Kinase, Yank1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      37604169..37874503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JJX8.2 GenPept UniProtKB/Swiss-Prot:Q9JJX8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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