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    CHLI2 magnesium chelatase i2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834633, updated on 7-Sep-2023

    Summary

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    Gene symbol
    CHLI2
    Gene description
    magnesium chelatase i2
    Primary source
    Araport:AT5G45930
    Locus tag
    AT5G45930
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CHL I2; CHL12; CHLI-2; K15I22.13; K15I22_13; magnesium chelatase i2; MAGNESIUM CHELATASE I2
    Summary
    encodes a second Chl I gene (CHLI2), a subunit of magnesium chelatase which is required for chlorophyll biosynthesis. Has ATPase activity, regulated by TRX-f. Involved in the assembly of the Mg chelatase complex.
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (18627950..18629697)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene nudix hydrolase homolog 11 Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Evolution aspects of intraspecific polymorphysm of Arabidopsis thaliana genes coding subunit I of Mg-chelatase complex]. Apchelimov AA, et al. Mol Biol (Mosk), 2009 Sep-Oct. PMID 19899639
    2. Arabidopsis CHLI2 can substitute for CHLI1. Huang YS, et al. Plant Physiol, 2009 Jun. PMID 19363094, Free PMC Article
    3. Functional analysis of Arabidopsis thaliana isoforms of the Mg-chelatase CHLI subunit. Kobayashi K, et al. Photochem Photobiol Sci, 2008 Oct. PMID 18846282
    4. The analysis of the ChlI 1 and ChlI 2 genes using acifluorfen-resistant mutant of Arabidopsis thaliana. Apchelimov AA, et al. Planta, 2007 Mar. PMID 17123104
    5. Chlorophyll biosynthesis. Expression of a second chl I gene of magnesium chelatase in Arabidopsis supports only limited chlorophyll synthesis. Rissler HM, et al. Plant Physiol, 2002 Feb. PMID 11842180, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Paths of evolutionary dynamics for CHLI 1 and CHLI 2 genes determining different forms of subunit I of Mg-chelatase complex of Arabidopsis thaliana are proposed.
      Title: [Evolution aspects of intraspecific polymorphysm of Arabidopsis thaliana genes coding subunit I of Mg-chelatase complex].
    2. CHLI2 could support some chlorophyll biosynthesis in the complete absence of CHLI1.
      Title: Arabidopsis CHLI2 can substitute for CHLI1.
    3. results reveal that although CHLI2 plays a limited role in chlorophyll biosynthesis, this subunit certainly contributes to the assembly of the Mg-chelatase complex
      Title: Functional analysis of Arabidopsis thaliana isoforms of the Mg-chelatase CHLI subunit.
    4. Comparison of the amino acid sequence of CHLI 1 and CHLI 2 encoded in the genome of acifluorfen herbicide resistant mutant aci5 and wild type revealed in particular alterations of the C-terminal end.
      Title: The analysis of the ChlI 1 and ChlI 2 genes using acifluorfen-resistant mutant of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_123961.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium chelatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chlorophyll biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within chlorophyll biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chlorophyll biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within chlorophyll biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of magnesium chelatase complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of magnesium chelatase complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    magnesium chelatase i2
    NP_199405.2
    • magnesium chelatase i2 (CHLI2); FUNCTIONS IN: magnesium chelatase activity, ATPase activity; INVOLVED IN: chlorophyll biosynthetic process; LOCATED IN: magnesium chelatase complex, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), Magnesium chelatase, ChlI subunit (InterPro:IPR000523), Magnesium chelatase, ATPase subunit I (InterPro:IPR011775); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT4G18480.1); Has 6443 Blast hits to 6440 proteins in 1624 species: Archae - 292; Bacteria - 4915; Metazoa - 3; Fungi - 0; Plants - 214; Viruses - 0; Other Eukaryotes - 1019 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      18627950..18629697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123961.4 → NP_199405.2  magnesium chelatase i2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199405.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XF33, Q8L712, Q9FJ43
      UniProtKB/TrEMBL
      A0A5S9YCI4, A0A7G2FHV5
      Conserved Domains (1) summary
      CHL00081
      Location:71 → 417
      chlI; Mg-protoporyphyrin IX chelatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XF33.1

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