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    Armc1 armadillo repeat containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 74252, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Armc1provided by MGI
    Official Full Name
    armadillo repeat containing 1provided by MGI
    Primary source
    MGI:MGI:1921502
    See related
    Ensembl:ENSMUSG00000027599 AllianceGenome:MGI:1921502
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arcp; 2310016N05Rik; 2900046P06Rik; 3110009G21Rik; C330014L16Rik
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in intracellular distribution of mitochondria. Located in mitochondrion. Orthologous to human ARMC1 (armadillo repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 11.8), bladder adult (RPKM 11.4) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Armc1 in Genome Data Viewer
    Location:
    3 A2; 3 5.36 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (19185566..19219225, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (19131402..19163095, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_07081 Neighboring gene predicted gene, 30789 Neighboring gene STARR-seq mESC enhancer starr_07082 Neighboring gene STARR-seq mESC enhancer starr_07083 Neighboring gene STARR-seq mESC enhancer starr_07084 Neighboring gene predicted gene, 30341 Neighboring gene STARR-seq mESC enhancer starr_07085 Neighboring gene STARR-seq mESC enhancer starr_07087 Neighboring gene STARR-positive B cell enhancer ABC_E334 Neighboring gene STARR-positive B cell enhancer ABC_E3427 Neighboring gene STARR-seq mESC enhancer starr_07090 Neighboring gene mitochondrial fission regulator 1 Neighboring gene STARR-seq mESC enhancer starr_07091 Neighboring gene RIKEN cDNA 3110037C07 gene Neighboring gene phosphodiesterase 7A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Armadillo-repeat protein functions: questions for little creatures. Tewari R, et al. Trends Cell Biol, 2010 Aug. PMID 20688255
    2. Cloning and expression of a novel armadillo motif containing gene in Xenopus. Chang JY, et al. Mech Dev, 2002 Dec. PMID 14516665
    3. The armadillo family of structural proteins. Hatzfeld M. Int Rev Cytol, 1999. PMID 9770300
    4. A global genomic transcriptional code associated with CNS-expressed genes. Bailey PJ, et al. Exp Cell Res, 2006 Oct 1. PMID 16919269
    5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular distribution of mitochondria ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    armadillo repeat-containing protein 1
    Names
    armadillo repeat containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357689.1 → NP_001344618.1  armadillo repeat-containing protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC127283, BF464987
      Conserved Domains (1) summary
      smart00185
      Location:32 → 67
      ARM; Armadillo/beta-catenin-like repeats

    2. NM_028840.3 → NP_083116.1  armadillo repeat-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_083116.1

      Status: VALIDATED

      Source sequence(s)
      AC127283, AK034483, AK082783, BF464987, BY165551
      Consensus CDS
      CCDS17255.1
      UniProtKB/Swiss-Prot
      Q8CBW1, Q9D7A8
      Related
      ENSMUSP00000029125.9, ENSMUST00000029125.10
      Conserved Domains (1) summary
      pfam00514
      Location:27 → 67
      Arm; Armadillo/beta-catenin-like repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      19185566..19219225 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252846.2 → XP_030108706.1  armadillo repeat-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8CBW1, Q9D7A8
      Conserved Domains (1) summary
      pfam00514
      Location:27 → 67
      Arm; Armadillo/beta-catenin-like repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D7A8.1 GenPept UniProtKB/Swiss-Prot:Q9D7A8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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